Literature DB >> 23539305

MCScanX-transposed: detecting transposed gene duplications based on multiple colinearity scans.

Yupeng Wang1, Jingping Li, Andrew H Paterson.   

Abstract

SUMMARY: Gene duplication occurs via different modes such as segmental and single-gene duplications. Transposed gene duplication, a specific form of single-gene duplication, 'copies' a gene from an ancestral chromosomal location to a novel location. MCScanX is a toolkit for detection and evolutionary analysis of gene colinearity. We have developed MCScanX-transposed, a software package to detect transposed gene duplications that occurred within different epochs, based on execution of MCScanX within and between related genomes. MCScanX-transposed can be also used for integrative analysis of gene duplication modes for a genome and to annotate a gene family of interest with gene duplication modes. AVAILABILITY: MCScanX-transposed is freely available at http://chibba.pgml.uga.edu/mcscan2/transposed/ SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Mesh：

Year:  2013        PMID： 23539305     DOI： 10.1093/bioinformatics/btt150

Source DB:  PubMed          Journal:  Bioinformatics        ISSN： 1367-4803            Impact factor:   6.937


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