Literature DB >> 23538876

Influence of percutaneous local therapy for hepatocellular carcinoma on gastric function.

Mitsuyoshi Kobayashi1, Fumihiko Kinekawa, Kazuya Matsuda, Shintaro Fujihara, Noriko Nishiyama, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Hideki Kobara, Akihiro Deguchi, Hirohito Yoneyama, Hirohito Mori, Tsutomu Masaki.   

Abstract

AIM: To investigate the influence of percutaneous local therapy on gastric myoelectrical activity in patients with hepatocellular carcinomas.
METHODS: Forty-four patients with hepatocellular carcinoma (HCC) [27 males and 17 females, ranging in age from 49 to 81 years old (69.7 ± 8.01 years)] who were admitted for percutaneous local therapy were enrolled in this study. We examined clinical abdominal symptoms using the Gastrointestinal Symptom Rating Scale (GSRS) before and 3 d after percutaneous local therapy. We also measured cutaneous fasting and postprandial electrogastrography (EGG) recordings before and 3 d after percutaneous local therapy.
RESULTS: We found that the percentage of normogastria in the fasting period was lower in the Child B group than in the Child A group (66.8% ± 8.6% vs 84.0% ± 3.8%). After percutaneous local therapy for HCC, the percentages of normogastria in the fasting period were significantly decreased (81.6% ± 3.5% vs 75.2% ± 4.5%). None of the postprandial EGG parameters changed significantly after percutaneous local therapy for HCC. Percutaneous local therapy for HCC reduced the power ratio (PR). In particular, the PR of tachygastria was significantly decreased after therapy (P < 0.01). However, no significant differences were found in the postprandial EGG parameters. Likewise, no significant differences were found in the calculated GSRS scores obtained from the questionnaire before and after therapy.
CONCLUSION: Gastric slow-wave dysrhythmias were induced by percutaneous local therapy in HCC patients, even though the GSRS scores obtained from the questionnaire did not change significantly.

Entities:  

Keywords:  Electrogastrography; Gastric myoelectrical activity; Hepatocellular carcinoma; Percutaneous ethanol injection; Radiofrequency ablation

Mesh:

Substances:

Year:  2013        PMID: 23538876      PMCID: PMC3602479          DOI: 10.3748/wjg.v19.i10.1618

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  35 in total

1.  Impaired postprandial gastric myoelectrical activity in Chinese patients with nonulcer dyspepsia.

Authors:  C L Lu; C Y Chen; F Y Chang; L J Kang; S D Lee; H C Wu; T S Kuo
Journal:  Dig Dis Sci       Date:  2001-02       Impact factor: 3.199

2.  Abnormal gastric slow waves in patients with functional dyspepsia assessed by multichannel electrogastrography.

Authors:  X Lin; J Z Chen
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2001-06       Impact factor: 4.052

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Authors:  Seishiro Watanabe; Kazutaka Kurokohchi; Tsutomu Masaki; Yoshiaki Miyauchi; Toshiharu Funaki; Hideyuki Inoue; Takashi Himoto; Yuko Kita; Naohito Uchida; Tetsuo Touge; Toshiaki Tatsukawa; Shigeki Kuriyama
Journal:  Int J Oncol       Date:  2004-02       Impact factor: 5.650

4.  The relationship between interdigestive gallbladder and gastroduodenal motility in man.

Authors:  M Kusano; T Sekiguchi; T Nishioka; O Kawamura; K Kikuchi; T Matsuzaki; T Horikoshi; S Kobayashi
Journal:  Gastroenterol Jpn       Date:  1990-10

5.  A migrating electric complex of canine small intestine.

Authors:  J H Szurszewski
Journal:  Am J Physiol       Date:  1969-12

6.  Abnormalities of the electrogastrogram in functional gastrointestinal disorders.

Authors:  A Leahy; K Besherdas; C Clayman; I Mason; O Epstein
Journal:  Am J Gastroenterol       Date:  1999-04       Impact factor: 10.864

Review 7.  Role of the gastric refluxate in gastroesophageal reflux disease: acid, weak acid and bile.

Authors:  Joel E Richter
Journal:  Am J Med Sci       Date:  2009-08       Impact factor: 2.378

8.  Combination therapy of percutaneous ethanol injection and radiofrequency ablation against hepatocellular carcinomas difficult to treat.

Authors:  Kazutataka Kurokohchi; Seishiro Watanabe; Tsutomu Masaki; Naoki Hosomi; Toshiharu Funaki; Keiji Arima; Shuhei Yoshida; Seiji Nakai; Masayuki Murota; Yoshiaki Miyauchi; Shigeki Kuriyama
Journal:  Int J Oncol       Date:  2002-09       Impact factor: 5.650

Review 9.  Diabetic gastropathy in patients with autonomic neuropathy.

Authors:  M Hongo; Y Okuno
Journal:  Diabet Med       Date:  1993       Impact factor: 4.359

10.  Mechanism of interdigestive migrating motor complex in conscious dogs.

Authors:  Hitoshi Nakajima; Erito Mochiki; Aaron Zietlow; Kirk Ludwig; Toku Takahashi
Journal:  J Gastroenterol       Date:  2009-12-25       Impact factor: 7.527

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