Literature DB >> 23538694

Adiponectin: an enlarging role in acute kidney injury.

Jieun Oh1, Hamid Rabb.   

Abstract

Adiponectin (APN) is known as an anti-inflammatory adipokine in obesity and atherosclerosis. Jin et al. examine the effects of APN deficiency in renal ischemia/reperfusion injury (IRI) using APN knockout mice and demonstrate that APN deficiency protects mice from IRI. This newly described role for APN in acute kidney injury opens up the possibility of novel mechanistic and therapeutic strategies from the cross-fertilization of the fields of obesity and kidney diseases.

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Year:  2013        PMID： 23538694     DOI： 10.1038/ki.2012.479

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  6 in total

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  6 in total

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