Literature DB >> 23538275

Role of the ubiquitin proteasome system in the heart.

Julia Pagan1, Tiffany Seto, Michele Pagano, Antonio Cittadini.   

Abstract

Proper protein turnover is required for cardiac homeostasis and, accordingly, impaired proteasomal function appears to contribute to heart disease. Specific proteasomal degradation mechanisms underlying cardiovascular biology and disease have been identified, and such cellular pathways have been proposed to be targets of clinical relevance. This review summarizes the latest literature regarding the specific E3 ligases involved in heart biology, and the general ways that the proteasome regulates protein quality control in heart disease. The potential for therapeutic intervention in Ubiquitin Proteasome System function in heart disease is discussed.

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Year:  2013        PMID： 23538275     DOI： 10.1161/CIRCRESAHA.112.300521

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   17.367


  49 in total

Review 1.  Proteotoxicity: an underappreciated pathology in cardiac disease.

Authors:  Marco Sandri; Jeffrey Robbins
Journal:  J Mol Cell Cardiol       Date:  2013-12-28       Impact factor: 5.000

2.  Cycloheximide Chase Analysis of Protein Degradation in Saccharomyces cerevisiae.

Authors:  Bryce W Buchanan; Michael E Lloyd; Sarah M Engle; Eric M Rubenstein
Journal:  J Vis Exp       Date:  2016-04-18       Impact factor: 1.355

3.  The role of ubiquitin in cardiac ischemia-reperfusion injury.

Authors:  Motoi Kobayashi; Jason K Higa; Takashi Matsui
Journal:  Am J Physiol Heart Circ Physiol       Date:  2019-01-18       Impact factor: 4.733

Review 4.  Cardiovascular Complications Associated with Multiple Myeloma Therapies: Incidence, Pathophysiology, and Management.

Authors:  Vivek G Patel; Robert F Cornell
Journal:  Curr Oncol Rep       Date:  2019-03-05       Impact factor: 5.075

Review 5.  Nuclear Factor (Erythroid-Derived 2)-Like 2 and Thioredoxin-1 in Atherosclerosis and Ischemia/Reperfusion Injury in the Heart.

Authors:  Philipp Jakobs; Vlad Serbulea; Norbert Leitinger; Anna Eckers; Judith Haendeler
Journal:  Antioxid Redox Signal       Date:  2017-01-18       Impact factor: 8.401

6.  Growth-based determination and biochemical confirmation of genetic requirements for protein degradation in Saccharomyces cerevisiae.

Authors:  Sheldon G Watts; Justin J Crowder; Samuel Z Coffey; Eric M Rubenstein
Journal:  J Vis Exp       Date:  2015-02-16       Impact factor: 1.355

7.  Identify potential drugs for cardiovascular diseases caused by stress-induced genes in vascular smooth muscle cells.

Authors:  Chien-Hung Huang; Jin-Shuei Ciou; Shun-Tsung Chen; Victor C Kok; Yi Chung; Jeffrey J P Tsai; Nilubon Kurubanjerdjit; Chi-Ying F Huang; Ka-Lok Ng
Journal:  PeerJ       Date:  2016-09-28       Impact factor: 2.984

8.  Sumo E2 enzyme UBC9 is required for efficient protein quality control in cardiomyocytes.

Authors:  Manish K Gupta; James Gulick; Ruijie Liu; Xuejun Wang; Jeffery D Molkentin; Jeffrey Robbins
Journal:  Circ Res       Date:  2014-08-05       Impact factor: 17.367

Review 9.  Proteasomal and lysosomal protein degradation and heart disease.

Authors:  Xuejun Wang; Jeffrey Robbins
Journal:  J Mol Cell Cardiol       Date:  2013-11-14       Impact factor: 5.000

Review 10.  Ubiquitin and Ubiquitin-like proteins in cardiac disease and protection.

Authors:  Jie Li; John A Johnson; Huabo Su
Journal:  Curr Drug Targets       Date:  2018       Impact factor: 3.465
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