Literature DB >> 23538072

Folate, vitamin B₁₂, and S-adenosylmethionine.

Teodoro Bottiglieri1.   

Abstract

Folate (vitamin B9) and cobalamin (vitamin B12) are essential for the normal development and function of the central nervous system. The metabolism of these vitamins is intimately linked and supports the synthesis of S-adenosylmethionine (SAMe), the major methyl group donor in methylation reactions. This article reviews the metabolic and clinical importance of folate, vitamin B12, and SAMe, as well as clinical trials in relation to depression and dementia.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID: 23538072     DOI: 10.1016/j.psc.2012.12.001

Source DB:  PubMed          Journal:  Psychiatr Clin North Am        ISSN: 0193-953X


  16 in total

1.  A Phase II Randomized, Controlled Trial of S-Adenosylmethionine in Reducing Serum α-Fetoprotein in Patients with Hepatitis C Cirrhosis and Elevated AFP.

Authors:  Timothy R Morgan; Kathryn Osann; Teodoro Bottiglieri; Neville Pimstone; John C Hoefs; Ke-Qin Hu; Tarek Hassanein; Thomas D Boyer; Lorene Kong; Wen-Pin Chen; Ellen Richmond; Rachel Gonzalez; Luz M Rodriguez; Frank L Meyskens
Journal:  Cancer Prev Res (Phila)       Date:  2015-06-30

Review 2.  [Nutrition and dietary supplements in psychiatric diseases].

Authors:  H Himmerich; F Erbguth
Journal:  Nervenarzt       Date:  2014-12       Impact factor: 1.214

Review 3.  S-Adenosylmethionine (SAMe) for Neuropsychiatric Disorders: A Clinician-Oriented Review of Research.

Authors:  Anup Sharma; Patricia Gerbarg; Teodoro Bottiglieri; Lila Massoumi; Linda L Carpenter; Helen Lavretsky; Philip R Muskin; Richard P Brown; David Mischoulon
Journal:  J Clin Psychiatry       Date:  2017-06       Impact factor: 4.384

4.  Association of Methionine to Homocysteine Status With Brain Magnetic Resonance Imaging Measures and Risk of Dementia.

Authors:  Babak Hooshmand; Helga Refsum; A David Smith; Grégoria Kalpouzos; Francesca Mangialasche; Christine A F von Arnim; Ingemar Kåreholt; Miia Kivipelto; Laura Fratiglioni
Journal:  JAMA Psychiatry       Date:  2019-11-01       Impact factor: 21.596

Review 5.  Review on Headache Related to Dietary Supplements.

Authors:  Shadi Ariyanfar; Soodeh Razeghi Jahromi; Mansoureh Togha; Zeinab Ghorbani
Journal:  Curr Pain Headache Rep       Date:  2022-03-07

Review 6.  Childhood adversity and epigenetic regulation of glucocorticoid signaling genes: Associations in children and adults.

Authors:  Audrey R Tyrka; Kathryn K Ridout; Stephanie H Parade
Journal:  Dev Psychopathol       Date:  2016-10-03

7.  Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex.

Authors:  James McKenna; David Kapfhamer; Jason M Kinchen; Brandi Wasek; Matthew Dunworth; Tracy Murray-Stewart; Teodoro Bottiglieri; Robert A Casero; Michael J Gambello
Journal:  Hum Mol Genet       Date:  2018-06-15       Impact factor: 6.150

Review 8.  S-Adenosyl Methionine and Transmethylation Pathways in Neuropsychiatric Diseases Throughout Life.

Authors:  Jin Gao; Catherine M Cahill; Xudong Huang; Joshua L Roffman; Stefania Lamon-Fava; Maurizio Fava; David Mischoulon; Jack T Rogers
Journal:  Neurotherapeutics       Date:  2018-01       Impact factor: 7.620

Review 9.  Methylation as a key regulator of Tau aggregation and neuronal health in Alzheimer's disease.

Authors:  Abhishek Ankur Balmik; Subashchandrabose Chinnathambi
Journal:  Cell Commun Signal       Date:  2021-05-07       Impact factor: 5.712

10.  Preliminary results of a randomized controlled trial carried out with a fixed combination of S-adenosyl-L-methionine and betaine versus amitriptyline in patients with mild depression.

Authors:  Francesco Di Pierro; Roberto Settembre
Journal:  Int J Gen Med       Date:  2015-02-04
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