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1. Antibody-drug conjugates for cancer: poised to deliver?

Authors: Bethan Hughes
Journal: Nat Rev Drug Discov Date: 2010-09 Impact factor: 84.694

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47 in total

1. Design, Synthesis and Application of Fluorine-Labeled Taxoids as ¹⁹F NMR Probes for the Metabolic Stability Assessment of Tumor-Targeted Drug Delivery Systems.

Authors: Joshua D Seitz; Jacob G Vineberg; Longfei Wei; Jonathan F Khan; Brendan Lichtenthal; Chi-Feng Lin; Iwao Ojima
Journal: J Fluor Chem Date: 2015-03-01 Impact factor: 2.050

2. Determination of Cellular Processing Rates for a Trastuzumab-Maytansinoid Antibody-Drug Conjugate (ADC) Highlights Key Parameters for ADC Design.

Authors: Katie F Maass; Chethana Kulkarni; Alison M Betts; K Dane Wittrup
Journal: AAPS J Date: 2016-02-24 Impact factor: 4.009

Review 3. Building better monoclonal antibody-based therapeutics.

Authors: George J Weiner
Journal: Nat Rev Cancer Date: 2015-06 Impact factor: 60.716

Review 4. Antibody Drug Conjugates: Application of Quantitative Pharmacology in Modality Design and Target Selection.

Authors: S Sadekar; I Figueroa; M Tabrizi
Journal: AAPS J Date: 2015-05-02 Impact factor: 4.009

5. A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.

Authors: Andrea E Prota; Katja Bargsten; J Fernando Diaz; May Marsh; Carmen Cuevas; Marc Liniger; Christian Neuhaus; Jose M Andreu; Karl-Heinz Altmann; Michel O Steinmetz
Journal: Proc Natl Acad Sci U S A Date: 2014-08-11 Impact factor: 11.205

6. Preparation of well-defined antibody-drug conjugates through glycan remodeling and strain-promoted azide-alkyne cycloadditions.

Authors: Xiuru Li; Tao Fang; Geert-Jan Boons
Journal: Angew Chem Int Ed Engl Date: 2014-05-23 Impact factor: 15.336

7. Strategic Incorporation of Fluorine into Taxoid Anticancer Agents for Medicinal Chemistry and Chemical Biology Studies.

Authors: Iwao Ojima
Journal: J Fluor Chem Date: 2017-01-03 Impact factor: 2.050

Review 8. Challenges and new frontiers in analytical characterization of antibody-drug conjugates.

Authors: Anil Wagh; Hangtian Song; Ming Zeng; Li Tao; Tapan K Das
Journal: MAbs Date: 2018-01-05 Impact factor: 5.857

9. Preclinical to Clinical Translation of Antibody-Drug Conjugates Using PK/PD Modeling: a Retrospective Analysis of Inotuzumab Ozogamicin.

Authors: Alison M Betts; Nahor Haddish-Berhane; John Tolsma; Paul Jasper; Lindsay E King; Yongliang Sun; Subramanyam Chakrapani; Boris Shor; Joseph Boni; Theodore R Johnson
Journal: AAPS J Date: 2016-05-19 Impact factor: 4.009

Review 10. HDX-MS guided drug discovery: small molecules and biopharmaceuticals.

Authors: David P Marciano; Venkatasubramanian Dharmarajan; Patrick R Griffin
Journal: Curr Opin Struct Biol Date: 2014-08-30 Impact factor: 6.809