Literature DB >> 23535329

Enantiocomplementary access to carba-analogs of C-nucleoside derivatives by recombinant Baeyer-Villiger monooxygenases.

Dario A Bianchi1, Roberto Moran-Ramallal, Naseem Iqbal, Florian Rudroff, Marko D Mihovilovic.   

Abstract

A novel and stereoselective synthetic route towards carba-C-nucleosides was investigated applying an enantiodivergent biooxidation strategy by two different Baeyer-Villiger monooxygenases. Within only three chemo-enzymatic steps it was possible to introduce four chiral centers starting from commercially available non-chiral starting material.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID: 23535329     DOI: 10.1016/j.bmcl.2013.02.085

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  3 in total

Review 1.  Flavoprotein monooxygenases for oxidative biocatalysis: recombinant expression in microbial hosts and applications.

Authors:  Romina D Ceccoli; Dario A Bianchi; Daniela V Rial
Journal:  Front Microbiol       Date:  2014-02-06       Impact factor: 5.640

2.  Cloning and characterization of the Type I Baeyer-Villiger monooxygenase from Leptospira biflexa.

Authors:  Romina D Ceccoli; Dario A Bianchi; Michael J Fink; Marko D Mihovilovic; Daniela V Rial
Journal:  AMB Express       Date:  2017-04-27       Impact factor: 3.298

3.  Cloning, expression and characterization of a versatile Baeyer-Villiger monooxygenase from Dietzia sp. D5.

Authors:  Serena Bisagni; Rajni Hatti-Kaul; Gashaw Mamo
Journal:  AMB Express       Date:  2014-03-20       Impact factor: 3.298

  3 in total

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