| Literature DB >> 23535329 |
Dario A Bianchi1, Roberto Moran-Ramallal, Naseem Iqbal, Florian Rudroff, Marko D Mihovilovic.
Abstract
A novel and stereoselective synthetic route towards carba-C-nucleosides was investigated applying an enantiodivergent biooxidation strategy by two different Baeyer-Villiger monooxygenases. Within only three chemo-enzymatic steps it was possible to introduce four chiral centers starting from commercially available non-chiral starting material.Entities:
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Year: 2013 PMID: 23535329 DOI: 10.1016/j.bmcl.2013.02.085
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823