Literature DB >> 2353066

A novel antibacterial diterpene from Premna schimperi.

S Habtemariam1, A I Gray, G W Halbert, P G Waterman.   

Abstract

A novel diterpene, (5R, 8R, 9S, 10R)-12-oxo-ent-3,13(16)-clerodien-15-oic acid, has been obtained from the leaves of Premna schimperi (Verbenaceae) using an anti-microbial bioassay-guided isolation procedure. The diterpene was identified on the basis of spectroscopic data and is active against the Gram-positive bacteria Staphylococcus aureus and Bacillus subtilis in the concentration range 20-25 micrograms ml-1.

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Year:  1990        PMID: 2353066     DOI: 10.1055/s-2006-960922

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  4 in total

Review 1.  Ethnomedicinal uses, phytochemistry and pharmacological aspects of the genus Premna: a review.

Authors:  Roza Dianita; Ibrahim Jantan
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

2.  In vitro antileishmanial effects of antibacterial diterpenes from two Ethiopian Premna species: P. schimperi and P. oligotricha.

Authors:  Solomon Habtemariam
Journal:  BMC Pharmacol       Date:  2003-06-06

3.  In vitro antimicrobial activity of plants used in traditional medicine in Gurage and Silti Zones, south central Ethiopia.

Authors:  Alemtshay Teka; Johana Rondevaldova; Zemede Asfaw; Sebsebe Demissew; Patrick Van Damme; Ladislav Kokoska; Wouter Vanhove
Journal:  BMC Complement Altern Med       Date:  2015-08-18       Impact factor: 3.659

Review 4.  Plant-Derived Anticancer Agents: Lessons from the Pharmacology of Geniposide and Its Aglycone, Genipin.

Authors:  Solomon Habtemariam; Giovanni Lentini
Journal:  Biomedicines       Date:  2018-03-26
  4 in total

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