Literature DB >> 23530512

Resveratrol: new avenues for a natural compound in neuroprotection.

Mercè Pallàs1, David Porquet, Alberto Vicente, Coral Sanfeliu.   

Abstract

This review summarizes the effects of resveratrol in neurodegenerative diseases and speculates on the direction the field will take in the immediate future. In particular, we emphasize studies on the effects of resveratrol on new pathways related to neurodegenerative diseases such as inflammatory processes, mitochondrial biogenesis and its control through gamma coactivator 1-α (PGC1α), and the role of the tandem sirtuin 1 (SIRT1) and AMP-activated protein kinase (AMPK) in neurodegeneration and in neurohormesis. While not all reported results are free from controversy, the demographic shift toward an older population makes compounds with this broad spectrum of potential clinical applications particularly interesting.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 23530512     DOI： 10.2174/1381612811319380005

Source DB:  PubMed          Journal:  Curr Pharm Des        ISSN： 1381-6128            Impact factor:   3.116


  27 in total

1.  Scrapie infection in experimental rodents and SMB-S15 cells decreased the brain endogenous levels and activities of Sirt1.

Authors:  Jing Wang; Jin Zhang; Qi Shi; Bao-Yun Zhang; Cao Chen; Li-Na Chen; Jing Sun; Hui Wang; Kang Xiao; Xiao-Ping Dong
Journal:  J Mol Neurosci       Date:  2014-11-13       Impact factor: 3.444

2.  Resveratrol (3, 5, 4'-Trihydroxy-trans-Stilbene) Attenuates a Mouse Model of Multiple Sclerosis by Altering the miR-124/Sphingosine Kinase 1 Axis in Encephalitogenic T Cells in the Brain.

Authors:  K Alexa Orr Gandy; Jiajia Zhang; Prakash Nagarkatti; Mitzi Nagarkatti
Journal:  J Neuroimmune Pharmacol       Date:  2019-04-02       Impact factor: 4.147

Review 3.  Interplay of drug metabolizing enzymes with cellular transporters.

Authors:  Michaela Böhmdorfer; Alexandra Maier-Salamon; Juliane Riha; Stefan Brenner; Martina Höferl; Walter Jäger
Journal:  Wien Med Wochenschr       Date:  2014-09-10

4.  Resveratrol Prevents the Cellular Damages Induced by Monocrotophos via PI3K Signaling Pathway in Human Cord Blood Mesenchymal Stem Cells.

Authors:  S Jahan; D Kumar; S Singh; V Kumar; A Srivastava; A Pandey; C S Rajpurohit; V K Khanna; A B Pant
Journal:  Mol Neurobiol       Date:  2018-03-10       Impact factor: 5.590

5.  Resveratrol Protects SAMP8 Brain Under Metabolic Stress: Focus on Mitochondrial Function and Wnt Pathway.

Authors:  V Palomera-Avalos; C Griñán-Ferré; D Puigoriol-Ilamola; A Camins; C Sanfeliu; A M Canudas; M Pallàs
Journal:  Mol Neurobiol       Date:  2016-02-12       Impact factor: 5.590

6.  In situ nanostructured hydrogel of resveratrol for brain targeting: in vitro-in vivo characterization.

Authors:  Amarjitsing Rajput; Aditi Bariya; Ahmed Allam; Sarah Othman; Shital B Butani
Journal:  Drug Deliv Transl Res       Date:  2018-10       Impact factor: 4.617

Review 7.  Oxidative and nitrative stress in neurodegeneration.

Authors:  Catherine A Cobb; Marsha P Cole
Journal:  Neurobiol Dis       Date:  2015-05-27       Impact factor: 5.996

Review 8.  Could Sirtuin Activities Modify ALS Onset and Progression?

Authors:  Bor Luen Tang
Journal:  Cell Mol Neurobiol       Date:  2016-12-10       Impact factor: 5.046

Review 9.  Duality of Antidepressants and Neuroprotectants.

Authors:  Yousef Tizabi
Journal:  Neurotox Res       Date:  2015-11-27       Impact factor: 3.911

10.  SIRT1 Overexpression in Mouse Hippocampus Induces Cognitive Enhancement Through Proteostatic and Neurotrophic Mechanisms.

Authors:  Rubén Corpas; Susana Revilla; Suzanna Ursulet; Marco Castro-Freire; Perla Kaliman; Valérie Petegnief; Lydia Giménez-Llort; Chamsy Sarkis; Mercè Pallàs; Coral Sanfeliu
Journal:  Mol Neurobiol       Date:  2016-09-10       Impact factor: 5.590
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.