Literature DB >> 2352838

Selective modulation of the cardiovascular response but not the antinociception evoked from the dorsal PAG, by 5-HT in the ventrolateral medulla.

T A Lovick1.   

Abstract

In lightly ananesthetised rats, electrical stimulation in the dorsal part of the periaqueductal grey matter (dPAG) produced an increase in the latency of the tail flick response accompanied by an increase in blood pressure and heart rate. Microinjection of 40-50nmol 5-HT bilaterally into the rostral part of nucleus paragigantocellularis lateralis (PGL) at the level of the facial nucleus attenuated the cardiovascular response to stimulation of the dPAG but had no effect on the analgesia. It is suggested that cardiovascular control neurones, but not the pain control neurones in the rostral part of PGL are subject to inhibitory serotonergic modulation.

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Year:  1990        PMID： 2352838     DOI： 10.1007/bf00370249

Source DB:  PubMed          Journal:  Pflugers Arch        ISSN： 0031-6768            Impact factor:   3.657


  9 in total

Review 1.  Integrated function of neurones in the rostral ventrolateral medulla.

Authors:  T A Lovick; P Li
Journal:  Prog Brain Res       Date:  1989       Impact factor: 2.453

2.  Anatomical evidence that hypertension associated with the defence reaction in the cat is mediated by a direct projection from a restricted portion of the midbrain periaqueductal grey to the subretrofacial nucleus of the medulla.

Authors:  P Carrive; R Bandler; R A Dampney
Journal:  Brain Res       Date:  1988-09-20       Impact factor: 3.252

3.  Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals.

Authors:  H W Steinbusch
Journal:  Neuroscience       Date:  1981       Impact factor: 3.590

4.  Cardiovascular responses to 5-HT in the ventrolateral medulla of the rat.

Authors:  T A Lovick
Journal:  J Auton Nerv Syst       Date:  1989-10

5.  Systemic and regional haemodynamic responses to microinjection of 5-HT agonists in the rostral ventrolateral medulla in the rat.

Authors:  T A Lovick
Journal:  Neurosci Lett       Date:  1989-12-15       Impact factor: 3.046

6.  Ventrolateral medullary lesions block the antinociceptive and cardiovascular responses elicited by stimulating the dorsal periaqueductal grey matter in rats.

Authors:  T A Lovick
Journal:  Pain       Date:  1985-03       Impact factor: 6.961

7.  Ventrolateral medullary pressor area: site of hypotensive and sympatho-inhibitory effects of (+/-)8-OH-DPAT in anaesthetized dogs.

Authors:  M Laubie; M Drouillat; H Dabiré; C Cherqui; H Schmitt
Journal:  Eur J Pharmacol       Date:  1989-02-07       Impact factor: 4.432

8.  Effect of activation of central nervous system serotonin 1A receptors on cardiorespiratory function.

Authors:  R A Gillis; K J Hill; J S Kirby; J A Quest; P Hamosh; W P Norman; K J Kellar
Journal:  J Pharmacol Exp Ther       Date:  1989-02       Impact factor: 4.030

9.  Apparent hyperalgesia after lesions of the descending serotonergic pathways is due to increased tail skin temperature.

Authors:  Arne Tjølsen; Odd-Geir Berge; Per Kristian Eide; Ole Jacob Broch; Kjell Hole
Journal:  Pain       Date:  1988-05       Impact factor: 6.961
  9 in total
  2 in total

1.  Upregulation of fatty acid amide hydrolase in the dorsal periaqueductal gray is associated with neuropathic pain and reduced heart rate in rats.

Authors:  Caron Dean; Cecilia J Hillard; Jeanne L Seagard; Francis A Hopp; Quinn H Hogan
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2017-02-01       Impact factor: 3.619

2.  Heterogeneity in patterns of pain development after nerve injury in rats and the influence of sex.

Authors:  Katherine Sherman; Victoria Woyach; James C Eisenach; Francis A Hopp; Freddy Cao; Quinn H Hogan; Caron Dean
Journal:  Neurobiol Pain       Date:  2021-07-24
  2 in total

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