Pratibha Singhi1, Anita Choudhary, Niranjan Khandelwal. 1. Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, 160017, India, doctorpratibhasinghi@gmail.com.
Abstract
OBJECTIVE: To assess the clinical spectrum and outcome of pediatric moyamoya disease (MMD) in Indian sub-continent. METHODS: The authors retrospectively analysed data of 23 patients, diagnosed with pediatric moyamoya disease from a single center during the period of 1996-2011. RESULTS: There were 18 boys and 5 girls. Mean age at onset of symptoms was 3.8 ± 2.2 y. All patients presented with cerebral ischemic events. Recurrent stroke was the presenting feature in 12(52.2 %) patients. Twenty one patients were definitive case of moyamoya disease and two were probable case of moyamoya disease. Posterior circulation was involved in 26.1 % patients. Three patients underwent indirect surgical revascularisation procedure and rest were managed conservatively. On follow up 66.6 % patients had residual neurological deficit. CONCLUSIONS: Heightened awareness of this entity among pediatric neurologists is required for early diagnosis of pediatric moyamoya disease.
OBJECTIVE: To assess the clinical spectrum and outcome of pediatric moyamoya disease (MMD) in Indian sub-continent. METHODS: The authors retrospectively analysed data of 23 patients, diagnosed with pediatric moyamoya disease from a single center during the period of 1996-2011. RESULTS: There were 18 boys and 5 girls. Mean age at onset of symptoms was 3.8 ± 2.2 y. All patients presented with cerebral ischemic events. Recurrent stroke was the presenting feature in 12(52.2 %) patients. Twenty one patients were definitive case of moyamoya disease and two were probable case of moyamoya disease. Posterior circulation was involved in 26.1 % patients. Three patients underwent indirect surgical revascularisation procedure and rest were managed conservatively. On follow up 66.6 % patients had residual neurological deficit. CONCLUSIONS: Heightened awareness of this entity among pediatric neurologists is required for early diagnosis of pediatric moyamoya disease.
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