Literature DB >> 2352549

Conversion of versiconal acetate to versiconal and versicolorin C in extracts from Aspergillus parasiticus.

J A Anderson1, C H Chung.   

Abstract

The primary product of hydrolysis of versiconal acetate catalyzed by porcine liver esterase and the 35-70% ammonium sulfate fraction from a soluble extract from mycelia of Aspergillus parasiticus was versiconal. Versiconal was stable at neutral pH for several hours and was rapidly converted to versicolorin C by treatment with 0.4 M HCl. The addition of NADPH to the 35-70% ammonium sulfate fraction resulted in conversion of versiconal acetate to both versiconal and versicolorin C. The conversion of versiconal acetate to versicolorin C in the cell-free system is proposed to involve an esterase and an NADPH-dependent cyclase.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2352549     DOI： 10.1007/bf00442767

Source DB:  PubMed          Journal:  Mycopathologia        ISSN： 0301-486X            Impact factor:   2.574


  8 in total

1.  INCORPORATION OF LABELLED COMPOUNDS INTO AFLATOXINS.

Authors:  J ADYE; R I MATELES
Journal:  Biochim Biophys Acta       Date:  1964-05-11

2.  Synthesis of versicolorin A by a mutant strain of Aspergillus parasiticus deficient in aflatoxin production.

Authors:  L S Lee; J W Bennett; A F Cucullu; J B Stanley
Journal:  J Agric Food Chem       Date:  1975 Nov-Dec       Impact factor: 5.279

Review 3.  Biosynthesis of aflatoxins.

Authors:  K K Maggon; S K Gupta; T A Venkitasubramanian
Journal:  Bacteriol Rev       Date:  1977-12

Review 4.  Enzymes and aflatoxin biosynthesis.

Authors:  M F Dutton
Journal:  Microbiol Rev       Date:  1988-06

5.  Enzymatic formation of the bisfuran structure in aflatoxin biosynthesis.

Authors:  N C Wan; D P Hsieh
Journal:  Appl Environ Microbiol       Date:  1980-01       Impact factor: 4.792

6.  Biosynthesis of versicolorin A.

Authors:  M S Anderson; M F Dutton
Journal:  Appl Environ Microbiol       Date:  1980-10       Impact factor: 4.792

7.  Metabolism of D-glucose in a wall-less mutant of Neurospora crassa examined by 13C and 31P nuclear magnetic resonances: effects of insulin.

Authors:  N J Greenfield; M A McKenzie; F Adebodun; F Jordan; J Lenard
Journal:  Biochemistry       Date:  1988-11-15       Impact factor: 3.162

8.  High aflatoxin production on a chemically defined medium.

Authors:  T V Reddy; L Viswanathan; T A Venkitasubramanian
Journal:  Appl Microbiol       Date:  1971-09
  8 in total
  8 in total

1.  Versicolorin A hemiacetal, hydroxydihydrosterigmatocystin, and aflatoxin G2 alpha reductase activity in extracts from Aspergillus parasiticus.

Authors:  J A Anderson; C H Chung; S H Cho
Journal:  Mycopathologia       Date:  1990-07       Impact factor: 2.574

2.  Enzymes in aflatoxin biosynthesis.

Authors:  J A Anderson
Journal:  World J Microbiol Biotechnol       Date:  1992-12       Impact factor: 3.312

3.  Stereochemistry during aflatoxin biosynthesis: cyclase reaction in the conversion of versiconal to versicolorin B and racemization of versiconal hemiacetal acetate.

Authors:  K Yabe; T Hamasaki
Journal:  Appl Environ Microbiol       Date:  1993-08       Impact factor: 4.792

4.  Aspergillus parasiticus cyclase catalyzes two dehydration steps in aflatoxin biosynthesis.

Authors:  Emi Sakuno; Ying Wen; Hidemi Hatabayashi; Hatsue Arai; Chiemi Aoki; Kimiko Yabe; Hiromitsu Nakajima
Journal:  Appl Environ Microbiol       Date:  2005-06       Impact factor: 4.792

5.  Cloning of a gene associated with aflatoxin B1 biosynthesis in Aspergillus parasiticus.

Authors:  P K Chang; C D Skory; J E Linz
Journal:  Curr Genet       Date:  1992-03       Impact factor: 3.886

6.  Isolation and characterization of a gene from Aspergillus parasiticus associated with the conversion of versicolorin A to sterigmatocystin in aflatoxin biosynthesis.

Authors:  C D Skory; P K Chang; J Cary; J E Linz
Journal:  Appl Environ Microbiol       Date:  1992-11       Impact factor: 4.792

7.  Stereochemistry during aflatoxin biosynthesis: conversion of norsolorinic acid to averufin.

Authors:  K Yabe; Y Matsuyama; Y Ando; H Nakajima; T Hamasaki
Journal:  Appl Environ Microbiol       Date:  1993-08       Impact factor: 4.792

8.  The Aspergillus parasiticus estA-encoded esterase converts versiconal hemiacetal acetate to versiconal and versiconol acetate to versiconol in aflatoxin biosynthesis.

Authors:  Perng-Kuang Chang; Kimiko Yabe; Jiujiang Yu
Journal:  Appl Environ Microbiol       Date:  2004-06       Impact factor: 4.792
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.