OBJECTIVES: To compare the ophthalmic artery Doppler indices observed in women with singleton pregnancies complicated by hypertension and to correlate the indices observed in hypertensive pregnant women with those observed in healthy pregnant women. METHODS: Ophthalmic artery Doppler indices were compared between 30 women with mild preeclampsia, 30 women with severe preeclampsia, and 30 women with chronic hypertension at 20 to 40 weeks' gestation. The control group consisted of 289 normotensive pregnant women. The resistive index, pulsatility index, and peak ratio were measured in the right eye. The mean and standard deviation were calculated for each group. Analysis of variance and the Tukey method were used to compare the means of the Doppler indices between groups. Receiver operating characteristic curves were used to determine the predictive power of the Doppler indices for identification of women with severe preeclampsia. P < .05 was considered statistically significant. RESULTS: Significant differences were found between the resistive index, pulsatility index, and peak ratio in women with severe preeclampsia compared to the other groups. The means ± SDs for the resistive index, pulsatility index, and pulse ratio in women with severe preeclampsia were 0.63 ± 0.09, 1.13 ± 0.31, and 0.89 ± 0.12, respectively. The optimal cutoff values for the resistive index, pulsatility index and the peak ratio for identification of women with severe preeclampsia were determined by the receiver operating characteristic curves to be 0.657, 1.318, and 0.784. CONCLUSIONS: Doppler imaging of the ophthalmic artery showed central overperfusion among pregnant women with severe preeclampsia. The peak ratio was the best index for discriminating between severe and mild preeclampsia or chronic hypertension.
OBJECTIVES: To compare the ophthalmic artery Doppler indices observed in women with singleton pregnancies complicated by hypertension and to correlate the indices observed in hypertensive pregnant women with those observed in healthy pregnant women. METHODS: Ophthalmic artery Doppler indices were compared between 30 women with mild preeclampsia, 30 women with severe preeclampsia, and 30 women with chronic hypertension at 20 to 40 weeks' gestation. The control group consisted of 289 normotensive pregnant women. The resistive index, pulsatility index, and peak ratio were measured in the right eye. The mean and standard deviation were calculated for each group. Analysis of variance and the Tukey method were used to compare the means of the Doppler indices between groups. Receiver operating characteristic curves were used to determine the predictive power of the Doppler indices for identification of women with severe preeclampsia. P < .05 was considered statistically significant. RESULTS: Significant differences were found between the resistive index, pulsatility index, and peak ratio in women with severe preeclampsia compared to the other groups. The means ± SDs for the resistive index, pulsatility index, and pulse ratio in women with severe preeclampsia were 0.63 ± 0.09, 1.13 ± 0.31, and 0.89 ± 0.12, respectively. The optimal cutoff values for the resistive index, pulsatility index and the peak ratio for identification of women with severe preeclampsia were determined by the receiver operating characteristic curves to be 0.657, 1.318, and 0.784. CONCLUSIONS: Doppler imaging of the ophthalmic artery showed central overperfusion among pregnant women with severe preeclampsia. The peak ratio was the best index for discriminating between severe and mild preeclampsia or chronic hypertension.
Authors: Fernanda Regina Giachini; Carlos Galaviz-Hernandez; Alicia E Damiano; Marta Viana; Angela Cadavid; Patricia Asturizaga; Enrique Teran; Sonia Clapes; Martin Alcala; Julio Bueno; María Calderón-Domínguez; María P Ramos; Victor Vitorino Lima; Martha Sosa-Macias; Nora Martinez; James M Roberts; Carlos Escudero Journal: Curr Hypertens Rep Date: 2017-10-06 Impact factor: 5.369
Authors: Márcia Aires Rodrigues de Freitas; Alice Vieira da Costa; Luciana Alves de Medeiros; Mario da Silva Garrote Filho; Angélica Lemos Debs Diniz; Nilson Penha-Silva Journal: Obstet Gynecol Int Date: 2018-03-01
Authors: Richard Busayo Olatunji; Ademola Joseph Adekanmi; Millicent Olubunmi Obajimi; Olumuyiwa Adebola Roberts; Temitope Olumuyiwa Ojo Journal: Int J Womens Health Date: 2015-07-20
Authors: Cristiane Alves Oliveira; Renato Augusto Moreira de Sa; Karina Vieira Zamprogno; Fabio Gutierrez da Matta; Flávia do Vale Araújo Journal: J Med Case Rep Date: 2017-11-20