Literature DB >> 23525274

Vinylic amino group activation: a new and general strategy leading to functionalized fused heteroaromatics.

Rajnikanth Sunke1, Raju Adepu, Ravikumar Kapavarapu, Swetha Chintala, Chandana Lakshmi Teja Meda, Kishore V L Parsa, Manojit Pal.   

Abstract

A conceptually new and general strategy has been developed for the construction of a benzimidazole or a benzoxazole ring fused with isoquinolinone affording a diverse and unique class of small molecules as potential and novel inhibitors of PDE4.

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Year:  2013        PMID： 23525274     DOI： 10.1039/c3cc41337c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Facile construction of fused benzimidazole-isoquinolinones that induce cell-cycle arrest and apoptosis in colorectal cancer cells.

Authors:  Liu-Jun He; Dong-Lin Yang; Shi-Qiang Li; Ya-Jun Zhang; Yan Tang; Jie Lei; Brendan Frett; Hui-Kuan Lin; Hong-Yu Li; Zhong-Zhu Chen; Zhi-Gang Xu
Journal:  Bioorg Med Chem       Date:  2018-06-12       Impact factor: 3.641

2.  A simple copper-catalyzed two-step one-pot synthesis of indolo[1,2-a]quinazoline.

Authors:  Chunpu Li; Lei Zhang; Shuangjie Shu; Hong Liu
Journal:  Beilstein J Org Chem       Date:  2014-10-21       Impact factor: 2.883

3.  Temperature controlled condensation of nitriles: efficient and convenient synthesis of β-enaminonitriles, 4-aminopyrimidines and 4-amidinopyrimidines in one system.

Authors:  Yinghua Li; Yingzu Zhu; Shiqun Xiang; Weibin Fan; Jiang Jin; Deguang Huang
Journal:  RSC Adv       Date:  2020-02-12       Impact factor: 3.361
  3 in total

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