Literature DB >> 23524938

Derivatization in liquid chromatography for mass spectrometric detection.

T Santa1.   

Abstract

Liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) has been frequently utilized for the sensitive and selective determination of the trace level compounds in biological samples. In LC/ESI-MS/MS, chemical derivatization is sometimes used to enhance the detection sensitivity of the analytes. This review presents an overview of the derivatization reagents in LC/ESI-MS/MS that have been applied to the low molecular weight compounds in recent five years (2008-2012).

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Year:  2013        PMID： 23524938     DOI： 10.5582/ddt.2013.v7.1.9

Source DB:  PubMed          Journal:  Drug Discov Ther        ISSN： 1881-7831


  4 in total

1.  A Unique Collision-Induced Dissociation Reaction of Cholamine Derivatives of Certain Prostaglandins.

Authors:  Dong Sun; Chong Su; Yingze Liu; Xiangjun Meng; John Paul Fawcett; Yingjie Guo; Jingkai Gu
Journal:  J Am Soc Mass Spectrom       Date:  2018-08-27       Impact factor: 3.109

2.  Establishment of a Charge Reversal Derivatization Strategy to Improve the Ionization Efficiency of Limaprost and Investigation of the Fragmentation Patterns of Limaprost Derivatives Via Exclusive Neutral Loss and Survival Yield Method.

Authors:  Dong Sun; Xiangjun Meng; Tianming Ren; John Paul Fawcett; Hualu Wang; Jingkai Gu
Journal:  J Am Soc Mass Spectrom       Date:  2018-04-09       Impact factor: 3.109

3.  Serum steroid profiling of hepatocellular carcinoma associated with hyperadrenocorticism in dogs: A preliminary study.

Authors:  Thandar Oo; Noboru Sasaki; Yoshinori Ikenaka; Takahiro Ichise; Noriyuki Nagata; Nozomu Yokoyama; Kazuyoshi Sasaoka; Keitaro Morishita; Kensuke Nakamura; Mitsuyoshi Takiguchi
Journal:  Front Vet Sci       Date:  2022-09-28

4.  Development of a Derivatization Reagent with a 2-Nitrophenylsulfonyl Moiety for UHPLC-HRMS/MS and Its Application to Detect Amino Acids Including Taurine.

Authors:  Shusuke Uekusa; Mayu Onozato; Tatsuya Sakamoto; Maho Umino; Hideaki Ichiba; Kenji Okoshi; Takeshi Fukushima
Journal:  Molecules       Date:  2021-06-08       Impact factor: 4.411
  4 in total

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