| Literature DB >> 23523712 |
S W Purkis1, V Troude, C A Hill.
Abstract
Two US blend style cigarette products, one ventilated, were smoked under 16 smoking regimes. 'Tar', nicotine, carbon monoxide (TNCO) and water smoke yields determined with these regimes, are shown to form part of continuous functions linked with puffing intensity (the product of puff volume and puff frequency) and total puff volume (the product of puff volume and puff number). This allows the prediction of yields for any regime and leads to the conclusion that the characterisation of cigarette products with these analytes is achievable from using a single smoking regime. The rate of increase of TNCO yields decreases as the puffing intensity increases, due to the more rapid burning of the tobacco available for smoking, although (particulate phase) water yield, relative to TNCO, increases considerably with intensity. Total puff volume is linearly related to TNCO machine yields from a range of regimes, to duplicated human yields and to the nicotine and solanesol retained in spent filters. The concentration of these smoke components is essentially independent of the regime used to generate them. This is not the case with water for which the yield in smoke increases exponentially with the total puff volume and its concentration increases rapidly with intensity.Entities:
Mesh:
Substances:
Year: 2013 PMID: 23523712 DOI: 10.1016/j.yrtph.2013.03.006
Source DB: PubMed Journal: Regul Toxicol Pharmacol ISSN: 0273-2300 Impact factor: 3.271