Literature DB >> 23522633

Dermocosmetic management of hyperpigmentations.

D Guerrero1.   

Abstract

Hyperpigmentations are very frequent situations that can have considerable impact on the quality of life of affected individuals. However, even if the esthetic prejudice they generate is undeniable, lentigo and melasma are benign conditions that require above all a risk-free management. In addition to the dermatological procedures (peeling, laser, etc.) and the topical drugs available to the dermatologist, there remains significant room for depigmenting dermocosmetic products. These products succeeded to transpose features of the classic pharmaceutical formula invented by Kligman from which they were inspired to the field of dermocosmetics. They comprise activators of epidermal turn-over, skin exfoliants, and active ingredients that interfere with the different stages of melanogenesis, without having the side effects of hydro quinone whose usage remains limited to the field of prescription drugs. Antioxidants are a particularly interesting addition because they participate in reducing cutaneous inflammation and efficiently complete the action of the other components of a depigmenting formula. It is important to remind the aggravating role that sun exposure has on hyperpigmentations. Therefore, measures of rigorous photoprotection are mandatory. Medical makeup, transitory or definite, is an interesting option for the management of hyperpigmentations. Consequently, depigmenting dermocosmetics, used in monotherapy but-most frequently- in combination with dermatological procedures, can be used in literally all types of hyperpigmentations with an efficacy that is dependent on the specific etiology. They are suited to be part of a treatment program that has to be adapted on a case-by-case basis.
Copyright © 2012 Elsevier Masson SAS. All rights reserved.

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Year:  2012        PMID: 23522633     DOI: 10.1016/S0151-9638(12)70130-8

Source DB:  PubMed          Journal:  Ann Dermatol Venereol        ISSN: 0151-9638            Impact factor:   0.777


  2 in total

1.  NF-κB/AP-1-targeted inhibition of macrophage-mediated inflammatory responses by depigmenting compound AP736 derived from natural 1,3-diphenylpropane skeleton.

Authors:  Van Thai Ha; Heung Soo Beak; Eunji Kim; Kwang-Soo Baek; Muhammad Jahangir Hossen; Woo Seok Yang; Yong Kim; Jun Ho Kim; Sungjae Yang; Jeong-Hwan Kim; Yung Hyup Joo; Chang Seok Lee; Joonho Choi; Hong-Ju Shin; Sungyoul Hong; Song Seok Shin; Jae Youl Cho
Journal:  Mediators Inflamm       Date:  2014-10-19       Impact factor: 4.711

2.  Facial primer provides immediate and long-term improvements in mild-to-moderate facial hyperpigmentation and fine lines associated with photoaging.

Authors:  Wendy E Roberts; Lily I Jiang; James H Herndon
Journal:  Clin Cosmet Investig Dermatol       Date:  2015-09-02
  2 in total

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