| Literature DB >> 23521882 |
Nilu Goonetilleke1, Andrew J McMichael.
Abstract
Ferguson et al. (2013) use applied physics to quantitate the fitness of HIV-1 Gag based on sequence variability across the protein. This enables a new approach to vaccine design that focuses CD8+ T cell responses on fitness-constrained parts of Gag.Entities:
Year: 2013 PMID： 23521882 DOI： 10.1016/j.immuni.2013.02.017
Source DB: PubMed Journal: Immunity ISSN： 1074-7613 Impact factor: 31.745