Literature DB >> 2351958

Cloning and molecular characterization of the murine herpesvirus 68 genome.

S Efstathiou1, Y M Ho, A C Minson.   

Abstract

Murine herpesvirus 68 (MHV-68) is a naturally occurring herpesvirus of small free-living rodents. In order to facilitate the molecular characterization of the virus genome, a library of cloned restriction fragments has been produced and restriction enzyme cleavage maps deduced for the enzymes BamHI, EcoRI and HindIII. The MHV-68 genome comprises a region of unique DNA of approximately 118 kbp which is flanked by variable numbers of a 1.23 kb repeat unit. The organization of the MHV-68 genome is, therefore, most similar to that of the lymphotropic gamma 2 group of herpesviruses which include herpesvirus saimiri and herpesvirus ateles.

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Year:  1990        PMID: 2351958     DOI: 10.1099/0022-1317-71-6-1355

Source DB:  PubMed          Journal:  J Gen Virol        ISSN: 0022-1317            Impact factor:   3.891


  85 in total

1.  Identification and initial characterization of the murine gammaherpesvirus 68 gene M3, encoding an abundantly secreted protein.

Authors:  V van Berkel; K Preiter; H W Virgin; S H Speck
Journal:  J Virol       Date:  1999-05       Impact factor: 5.103

2.  CD4(+) T cell-mediated control of a gamma-herpesvirus in B cell-deficient mice is mediated by IFN-gamma.

Authors:  J P Christensen; R D Cardin; K C Branum; P C Doherty
Journal:  Proc Natl Acad Sci U S A       Date:  1999-04-27       Impact factor: 11.205

3.  Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells.

Authors:  K E Weck; S S Kim; I V Virgin HW; S H Speck
Journal:  J Virol       Date:  1999-04       Impact factor: 5.103

4.  Murine gammaherpesvirus 68 cyclin D homologue is required for efficient reactivation from latency.

Authors:  A T Hoge; S B Hendrickson; W H Burns
Journal:  J Virol       Date:  2000-08       Impact factor: 5.103

5.  Complete sequence and genomic analysis of murine gammaherpesvirus 68.

Authors:  H W Virgin; P Latreille; P Wamsley; K Hallsworth; K E Weck; A J Dal Canto; S H Speck
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

6.  Stimulation via CD40 can substitute for CD4 T cell function in preventing reactivation of a latent herpesvirus.

Authors:  S R Sarawar; B J Lee; S K Reiter; S P Schoenberger
Journal:  Proc Natl Acad Sci U S A       Date:  2001-05-15       Impact factor: 11.205

Review 7.  The latency-associated nuclear antigen, a multifunctional protein central to Kaposi's sarcoma-associated herpesvirus latency.

Authors:  Mary E Ballestas; Kenneth M Kaye
Journal:  Future Microbiol       Date:  2011-12       Impact factor: 3.165

8.  Construction and characterization of an infectious murine gammaherpesivrus-68 bacterial artificial chromosome.

Authors:  Ting-Ting Wu; Hsiang-I Liao; Leming Tong; Ronika Sitapara Leang; Greg Smith; Ren Sun
Journal:  J Biomed Biotechnol       Date:  2010-12-09

9.  Induction of protective immunity against murine gammaherpesvirus 68 infection in the absence of viral latency.

Authors:  Qingmei Jia; Michael L Freeman; Eric J Yager; Ian McHardy; Leming Tong; DeeAnn Martinez-Guzman; Tammy Rickabaugh; Seungmin Hwang; Marcia A Blackman; Ren Sun; Ting-Ting Wu
Journal:  J Virol       Date:  2009-12-16       Impact factor: 5.103

10.  Primary clearance of murine gammaherpesvirus 68 by PKCtheta-/- CD8 T cells is compromised in the absence of help from CD4 T cells.

Authors:  Peter Dias; Ashley L Shea; Chandra Inglis; Francesca Giannoni; Lian Ni Lee; Sally R Sarawar
Journal:  J Virol       Date:  2008-09-25       Impact factor: 5.103

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