Literature DB >> 23519510

Familial hypercholesterolaemia presenting with coronary artery disease in a young patient.

K S Subramani1, Vikram B Kolhari, C N Manjunath, Shivkumar Bhairappa.   

Abstract

A man in his early 20s presented with an angina on exertion and postprandial angina. Upon examination, the patient had carotid artery bruit and multiple tendon xanthomas. His lipid profile showed a very high total and low-density lipoprotein cholesterol; treadmill test was strongly positive. Subsequent coronary angiogram revealed triple vessel disease. The patient underwent revascularisation and is on lipid lowering therapy.

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Mesh：

Year:  2013        PMID： 23519510      PMCID： PMC3618795          DOI： 10.1136/bcr-2013-008718

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  8 in total

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Journal:  BMJ       Date:  1991-10-12

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Journal:  Am J Cardiol       Date:  1998-12-15       Impact factor: 2.778

8.  An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes.

Authors:  Liwen Zhang; Timothy McCabe; Jon H Condra; Yan G Ni; Laurence B Peterson; Weirong Wang; Alison M Strack; Fubao Wang; Shilpa Pandit; Holly Hammond; Dana Wood; Dale Lewis; Ray Rosa; Vivienne Mendoza; Anne Marie Cumiskey; Douglas G Johns; Barbara C Hansen; Xun Shen; Neil Geoghagen; Kristian Jensen; Lei Zhu; Karol Wietecha; Douglas Wisniewski; Lingyi Huang; Jing Zhang Zhao; Robin Ernst; Richard Hampton; Peter Haytko; Frances Ansbro; Shannon Chilewski; Jayne Chin; Lyndon J Mitnaul; Andrea Pellacani; Carl P Sparrow; Zhiqiang An; William Strohl; Brian Hubbard; Andrew S Plump; Daniel Blom; Ayesha Sitlani
Journal:  Int J Biol Sci       Date:  2012-02-09       Impact factor: 6.580
  8 in total
  1 in total

1.  Familial hypercholesterolemia in an Iranian family due to a mutation in the APOE gene (first case report).

Authors:  Shahab Noorian; Rezvan Razmandeh; Roshanak Jazayeri
Journal:  J Diabetes Metab Disord       Date:  2022-03-10
  1 in total

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