Literature DB >> 23518186

Persistence of Klebsiella pneumoniae clones with OXA-48 or NDM carbapenemases causing bacteraemias in a Riyadh hospital.

Mohamed H Al-Agamy1, Atef M Shibl, Noura A Elkhizzi, Daniele Meunier, Jane F Turton, David M Livermore.   

Abstract

We characterized nine carbapenem-resistant Klebsiella pneumoniae collected over 9 months during 2011 in Riyadh; 8 from Hospital A and 1 from Hospital B. Variable number tandem repeat (VNTR) defined three strains at Hospital A, each with 2 or 3 representatives recovered from separate patients over periods of 6-24 weeks; 2 strains had OXA-48 and 1 had NDM. The single isolate from Hospital B also had OXA-48 but was distinct by VNTR from the Hospital A strains. Two strains with OXA-48 were colistin resistant; the third included a colistin-resistant representative from a colistin-treated patient.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID: 23518186     DOI: 10.1016/j.diagmicrobio.2013.02.006

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN: 0732-8893            Impact factor:   2.803


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