Literature DB >> 23514174

Metabolomics in nutrition research: current status and perspectives.

Lorraine Brennan1.   

Abstract

Metabolomics is the study of metabolites present in biological samples such as biofluids, tissue/cellular extracts and culture media. Combining metabolomic data with multivariate data analysis tools allows us to study alterations in metabolic pathways following different perturbations. Examples of perturbations can be disease state, drug or nutritional interventions with successful applications in the fields of drug toxicology, biomarker development and nutrition research. Application of metabolomics to nutrition research is increasing and applications range from assessing novel biomarkers of dietary intake to application of metabolomics in intervention studies. The present review highlights the use of metabolomics in nutrition research.

Mesh：

Year:  2013        PMID： 23514174     DOI： 10.1042/BST20120350

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


  21 in total

1.  Metabolomics identifies changes in fatty acid and amino acid profiles in serum of overweight older adults following a weight loss intervention.

Authors:  A Perez-Cornago; L Brennan; I Ibero-Baraibar; H H M Hermsdorff; A O'Gorman; M A Zulet; J Alfredo Martínez
Journal:  J Physiol Biochem       Date:  2014-01-09       Impact factor: 4.158

Review 2.  Holistic Analysis Enhances the Description of Metabolic Complexity in Dietary Natural Products.

Authors:  Charlotte Simmler; Daniel Kulakowski; David C Lankin; James B McAlpine; Shao-Nong Chen; Guido F Pauli
Journal:  Adv Nutr       Date:  2016-01       Impact factor: 8.701

3.  Multiplatform metabolomic fingerprinting as a tool for understanding hypercholesterolemia in Wistar rats.

Authors:  Diana González-Peña; Danuta Dudzik; Clara Colina-Coca; Begoña de Ancos; Antonia García; Coral Barbas; Concepción Sánchez-Moreno
Journal:  Eur J Nutr       Date:  2015-05-13       Impact factor: 5.614

4.  Targeted plasma metabolome response to variations in dietary glycemic load in a randomized, controlled, crossover feeding trial in healthy adults.

Authors:  Sally Barton; Sandi L Navarro; Matthew F Buas; Yvonne Schwarz; Haiwei Gu; Danijel Djukovic; Daniel Raftery; Mario Kratz; Marian L Neuhouser; Johanna W Lampe
Journal:  Food Funct       Date:  2015-09       Impact factor: 5.396

5.  Systems toxicology: from basic research to risk assessment.

Authors:  Shana J Sturla; Alan R Boobis; Rex E FitzGerald; Julia Hoeng; Robert J Kavlock; Kristin Schirmer; Maurice Whelan; Martin F Wilks; Manuel C Peitsch
Journal:  Chem Res Toxicol       Date:  2014-01-21       Impact factor: 3.739

Review 6.  Modeling-Enabled Systems Nutritional Immunology.

Authors:  Meghna Verma; Raquel Hontecillas; Vida Abedi; Andrew Leber; Nuria Tubau-Juni; Casandra Philipson; Adria Carbo; Josep Bassaganya-Riera
Journal:  Front Nutr       Date:  2016-02-16

Review 7.  Studies on Modulation of Gut Microbiota by Wine Polyphenols: From Isolated Cultures to Omic Approaches.

Authors:  Montserrat Dueñas; Carolina Cueva; Irene Muñoz-González; Ana Jiménez-Girón; Fernando Sánchez-Patán; Celestino Santos-Buelga; M Victoria Moreno-Arribas; Begoña Bartolomé
Journal:  Antioxidants (Basel)       Date:  2015-01-05

Review 8.  Nutrigenomics, the Microbiome, and Gene-Environment Interactions: New Directions in Cardiovascular Disease Research, Prevention, and Treatment: A Scientific Statement From the American Heart Association.

Authors:  Jane F Ferguson; Hooman Allayee; Robert E Gerszten; Folami Ideraabdullah; Penny M Kris-Etherton; José M Ordovás; Eric B Rimm; Thomas J Wang; Brian J Bennett
Journal:  Circ Cardiovasc Genet       Date:  2016-04-19

9.  Effects of whole grain, fish and bilberries on serum metabolic profile and lipid transfer protein activities: a randomized trial (Sysdimet).

Authors:  Maria Lankinen; Marjukka Kolehmainen; Tiina Jääskeläinen; Jussi Paananen; Laura Joukamo; Antti J Kangas; Pasi Soininen; Kaisa Poutanen; Hannu Mykkänen; Helena Gylling; Matej Orešič; Matti Jauhiainen; Mika Ala-Korpela; Matti Uusitupa; Ursula Schwab
Journal:  PLoS One       Date:  2014-02-28       Impact factor: 3.240

10.  The Karlsruhe Metabolomics and Nutrition (KarMeN) Study: Protocol and Methods of a Cross-Sectional Study to Characterize the Metabolome of Healthy Men and Women.

Authors:  Achim Bub; Anita Kriebel; Claudia Dörr; Susanne Bandt; Manuela Rist; Alexander Roth; Eva Hummel; Sabine Kulling; Ingrid Hoffmann; Bernhard Watzl
Journal:  JMIR Res Protoc       Date:  2016-07-15
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