Literature DB >> 23512775

Antioxidant effect of astragalin isolated from the leaves of Morus alba L. against free radical-induced oxidative hemolysis of human red blood cells.

Jiwon Choi1, Hyun Ju Kang, Sung Zoo Kim, Tae Oh Kwon, Seung-Il Jeong, Seon Il Jang.   

Abstract

We evaluated the antioxidant properties of mulberry leaves extract (MLE) and flavonoids isolated from MLE. MLE was prepared by extraction with methanol. Flavonoids were analyzed by high-performance liquid chromatography. Oxidative hemolysis of normal human red blood cells (RBCs) was induced by the aqueous peroxyl radical [2,2'-Azobis (2-amidinopropane) dihydrochloride, AAPH]. MLE contained three flavonoids in the order quercetin (QC) > kaempferol (KF) > astragalin (AG). Oxidative hemolysis of RBCs induced by AAPH was suppressed by MLE, AG, KF, and QC in a time- and dose-dependent manner. MLE and these three flavonoids prevented the depletion of cystosolic antioxidant glutathione (GSH) in RBCs. AG had the greatest protective effect against AAPH-induced oxidative hemolysis and GSH depletion in RBCs.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 23512775     DOI： 10.1007/s12272-013-0090-x

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  17 in total

1.  Mulberry leaf polyphenols delay aging and regulate fat metabolism via the germline signaling pathway in Caenorhabditis elegans.

Authors:  Shanqing Zheng; Sentai Liao; Yuxiao Zou; Zhi Qu; Weizhi Shen; Ying Shi
Journal:  Age (Dordr)       Date:  2014-10-17

2.  Antioxidant activities and polyphenol content of Morus alba leaf extracts collected from varying regions.

Authors:  Dong-Seon Kim; Young Min Kang; Wen Yi Jin; Yoon-Young Sung; Goya Choi; Ho Kyoung Kim
Journal:  Biomed Rep       Date:  2014-06-06

3.  Sequencing, De novo Assembly, Functional Annotation and Analysis of Phyllanthus amarus Leaf Transcriptome Using the Illumina Platform.

Authors:  Aparupa Bose Mazumdar; Sharmila Chattopadhyay
Journal:  Front Plant Sci       Date:  2016-01-28       Impact factor: 5.753

4.  Astragalin-induced cell death is caspase-dependent and enhances the susceptibility of lung cancer cells to tumor necrosis factor by inhibiting the NF-кB pathway.

Authors:  Minghui Chen; Fangfang Cai; Daolong Zha; Xueshi Wang; Wenjing Zhang; Yan He; Qilai Huang; Hongqin Zhuang; Zi-Chun Hua
Journal:  Oncotarget       Date:  2017-04-18

Review 5.  Astragalin: A Bioactive Phytochemical with Potential Therapeutic Activities.

Authors:  Ammara Riaz; Azhar Rasul; Ghulam Hussain; Muhammad Kashif Zahoor; Farhat Jabeen; Zinayyera Subhani; Tahira Younis; Muhammad Ali; Iqra Sarfraz; Zeliha Selamoglu
Journal:  Adv Pharmacol Sci       Date:  2018-05-02

6.  Hepatoprotective potential of Malvaviscus arboreus against carbon tetrachloride-induced liver injury in rats.

Authors:  Omnia Hesham Abdelhafez; Michael Atef Fawzy; John Refaat Fahim; Samar Yehia Desoukey; Markus Krischke; Martin J Mueller; Usama Ramadan Abdelmohsen
Journal:  PLoS One       Date:  2018-08-23       Impact factor: 3.240

7.  Mulberry leaf powder regulates antioxidative capacity and lipid metabolism in finishing pigs.

Authors:  Yingying Liu; Yinghui Li; Yi Xiao; Yinglin Peng; Jianhua He; Chen Chen; Dingfu Xiao; Yulong Yin; Fengna Li
Journal:  Anim Nutr       Date:  2020-12-18

8.  Effect of ensiled mulberry leaves and sun-dried mulberry fruit pomace on finishing steer growth performance, blood biochemical parameters, and carcass characteristics.

Authors:  Zhenming Zhou; Bo Zhou; Liping Ren; Qingxiang Meng
Journal:  PLoS One       Date:  2014-01-10       Impact factor: 3.240

9.  Antihemolytic Activities of Green Tea, Safflower, and Mulberry Extracts during Plasmodium berghei Infection in Mice.

Authors:  Suthin Audomkasok; Waraporn Singpha; Sukanya Chachiyo; Voravuth Somsak
Journal:  J Pathog       Date:  2014-11-18

10.  In vitro Screening for Antioxidant, Antimicrobial, and Antidiabetic Properties of Some Korean Native Plants on Mt. Halla, Jeju Island.

Authors:  T K Hyun; H C Kim; J S Kim
Journal:  Indian J Pharm Sci       Date:  2015 Nov-Dec       Impact factor: 0.975
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.