Literature DB >> 23512751

Identification of cystathionine β-synthase inhibitors using a hydrogen sulfide selective probe.

Megan K Thorson1, Tomas Majtan, Jan P Kraus, Amy M Barrios.   

Abstract

Buzzing with activity: A hydrogen sulfide selective fluorogenic probe, 7-azido-4-methylcoumarin (AzMC), serves as a highly sensitive assay for cystathionine β-synthase activity, and is suitable for the high-throughput discovery of novel enzyme inhibitors.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2013        PMID： 23512751     DOI： 10.1002/anie.201300841

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  49 in total

1.  Chemiluminescent detection of enzymatically produced H2S.

Authors:  T Spencer Bailey; Michael D Pluth
Journal:  Methods Enzymol       Date:  2015-01-10       Impact factor: 1.600

2.  H2S donors with optical responses.

Authors:  Michael D Pluth; Yu Zhao; Matthew M Cerda
Journal:  Methods Enzymol       Date:  2020-06-15       Impact factor: 1.600

3.  A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer?

Authors:  Xu Cao; Lei Ding; Zhi-Zhong Xie; Yong Yang; Matthew Whiteman; Philip K Moore; Jin-Song Bian
Journal:  Antioxid Redox Signal       Date:  2018-06-29       Impact factor: 8.401

4.  Time-Gated Detection of Cystathionine γ-Lyase Activity and Inhibition with a Selective, Luminogenic Hydrogen Sulfide Sensor.

Authors:  Yao Yao; Chen Kong; Liang Yin; Atul D Jain; Kiira Ratia; Gregory R J Thatcher; Terry W Moore; Tom G Driver; Lawrence W Miller
Journal:  Chemistry       Date:  2016-11-25       Impact factor: 5.236

5.  AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro.

Authors:  Bartosz Szczesny; Katalin Módis; Kazunori Yanagi; Ciro Coletta; Sophie Le Trionnaire; Alexis Perry; Mark E Wood; Matthew Whiteman; Csaba Szabo
Journal:  Nitric Oxide       Date:  2014-04-19       Impact factor: 4.427

6.  Time-Gated Luminescence Detection of Enzymatically Produced Hydrogen Sulfide: Design, Synthesis, and Application of a Lanthanide-Based Probe.

Authors:  Yao Yao; Loruhama Delgado-Rivera; Hamid Samareh Afsari; Liang Yin; Gregory R J Thatcher; Terry W Moore; Lawrence W Miller
Journal:  Inorg Chem       Date:  2017-12-27       Impact factor: 5.165

Review 7.  Cystathionine-β-Synthase: Molecular Regulation and Pharmacological Inhibition.

Authors:  Karim Zuhra; Fiona Augsburger; Tomas Majtan; Csaba Szabo
Journal:  Biomolecules       Date:  2020-04-30

Review 8.  Activity-Based Sensing: A Synthetic Methods Approach for Selective Molecular Imaging and Beyond.

Authors:  Kevin J Bruemmer; Steven W M Crossley; Christopher J Chang
Journal:  Angew Chem Int Ed Engl       Date:  2020-04-23       Impact factor: 15.336

9.  Chemiluminescent detection of enzymatically produced hydrogen sulfide: substrate hydrogen bonding influences selectivity for H2S over biological thiols.

Authors:  T Spencer Bailey; Michael D Pluth
Journal:  J Am Chem Soc       Date:  2013-11-06       Impact factor: 15.419

Review 10.  Chemical Biology of H2S Signaling through Persulfidation.

Authors:  Milos R Filipovic; Jasmina Zivanovic; Beatriz Alvarez; Ruma Banerjee
Journal:  Chem Rev       Date:  2017-11-07       Impact factor: 60.622
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