Annular pustular psoriasis associated with affective psychosis.

An eighty-year-old man presented with recurrent annular erythema with pustules on the axillae, trunk, and groin consistent with a diagnosis of annular pustular psoriasis. Over the years, exacerbations of his skin lesions directly followed manic episodes. Use of major tranquilizers, including chlorpromazine, brought about a favorable remission of both the manic symptoms and the cutaneous lesions.