Siegfried Mense1, Ulrich Hoheisel. 1. Department of Neurophysiology, Centre for Biomedicine and Medical Technology Mannheim, Ruprecht Karls University Heidelberg, Ludolf Krehl Strasse 13-17, 68167 Mannheim, Germany. siegfried.mense@medma.uni-heidelberg.de
Abstract
INTRODUCTION: The aims of the experiments were to: (1) determine whether low-energy shock wave treatment accelerates the recovery of muscle sensitivity and functionality after a nerve lesion; and (2) assess the effect of shock waves on the regeneration of injured nerve fibers. METHODS: After compression of a muscle nerve in rats the effects of shock wave treatment on the sequelae of the lesion were tested. In non-anesthetized animals, pressure pain thresholds and exploratory activity were determined. The influence of the treatment on the distance of nerve regeneration was studied in immunohistochemical experiments. RESULTS: Both behavioral and immunohistochemical data show that shock wave treatment accelerates the recovery of muscle sensitivity and functionality and promotes regeneration of injured nerve fibers. CONCLUSION: Treatment with focused shock waves induces an improvement of nerve regeneration in a rodent model of nerve compression.
INTRODUCTION: The aims of the experiments were to: (1) determine whether low-energy shock wave treatment accelerates the recovery of muscle sensitivity and functionality after a nerve lesion; and (2) assess the effect of shock waves on the regeneration of injured nerve fibers. METHODS: After compression of a muscle nerve in rats the effects of shock wave treatment on the sequelae of the lesion were tested. In non-anesthetized animals, pressure pain thresholds and exploratory activity were determined. The influence of the treatment on the distance of nerve regeneration was studied in immunohistochemical experiments. RESULTS: Both behavioral and immunohistochemical data show that shock wave treatment accelerates the recovery of muscle sensitivity and functionality and promotes regeneration of injured nerve fibers. CONCLUSION: Treatment with focused shock waves induces an improvement of nerve regeneration in a rodent model of nerve compression.
Authors: Kamal Mezian; Jakub Jačisko; Radek Kaiser; Stanislav Machač; Petra Steyerová; Karolína Sobotová; Yvona Angerová; Ondřej Naňka Journal: Front Neurol Date: 2021-05-14 Impact factor: 4.003
Authors: Alex K Wu; Xiaoyu Zhang; Jianwen Wang; Hongxiu Ning; Uwais Zaid; Jaqueline D Villalta; Guifang Wang; Lia Banie; Guiting Lin; Tom F Lue Journal: Transl Androl Urol Date: 2018-03
Authors: Simeon C Daeschler; Leila Harhaus; Philipp Schoenle; Arne Boecker; Ulrich Kneser; Konstantin D Bergmeister Journal: Sci Rep Date: 2018-02-16 Impact factor: 4.379