Literature DB >> 2350174

Purification and characterization of mouse liver xanthine oxidase.

G Carpani1, M Racchi, P Ghezzi, M Terao, E Garattini.   

Abstract

Xanthine oxidase (EC 1.1.3.22) is purified to homogeneity from mouse liver after induction with bacterial lipopolysaccharide. The enzyme has an apparent molecular weight of 300,000 in its native state and it is suggested to be constituted of two identical subunits of Mr 150,000 each. The isoelectric point is 6.7 and the apparent Km value for xanthine is 3.4 microM. The amino acid composition of mouse xanthine oxidase is quite similar to that of Drosophila xanthine dehydrogenase.

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Year:  1990        PMID： 2350174     DOI： 10.1016/0003-9861(90)90487-j

Source DB:  PubMed          Journal:  Arch Biochem Biophys        ISSN： 0003-9861            Impact factor:   4.013


  11 in total

1.  The role of xanthine oxidase in platelet activating factor induced intestinal injury in the rat.

Authors:  X W Qu; R A Rozenfeld; W Huang; G B Bulkley; W Hsueh
Journal:  Gut       Date:  1999-02       Impact factor: 23.059

2.  Molecular cloning of a cDNA coding for mouse liver xanthine dehydrogenase. Regulation of its transcript by interferons in vivo.

Authors:  M Terao; G Cazzaniga; P Ghezzi; M Bianchi; F Falciani; P Perani; E Garattini
Journal:  Biochem J       Date:  1992-05-01       Impact factor: 3.857

3.  Expression of xanthine oxidoreductase in mouse mammary epithelium during pregnancy and lactation: regulation of gene expression by glucocorticoids and prolactin.

Authors:  M Kurosaki; S Zanotta; M Li Calzi; E Garattini; M Terao
Journal:  Biochem J       Date:  1996-11-01       Impact factor: 3.857

Review 4.  Mammalian molybdo-flavoenzymes, an expanding family of proteins: structure, genetics, regulation, function and pathophysiology.

Authors:  Enrico Garattini; Ralf Mendel; Maria João Romão; Richard Wright; Mineko Terao
Journal:  Biochem J       Date:  2003-05-15       Impact factor: 3.857

5.  Interferons induce xanthine dehydrogenase gene expression in L929 cells.

Authors:  F Falciani; P Ghezzi; M Terao; G Cazzaniga; E Garattini
Journal:  Biochem J       Date:  1992-08-01       Impact factor: 3.857

6.  Molybdenum(VI) salts convert the xanthine oxidoreductase apoprotein into the active enzyme in mouse L929 fibroblastic cells.

Authors:  F Falciani; M Terao; S Goldwurm; A Ronchi; A Gatti; C Minoia; M Li Calzi; M Salmona; G Cazzaniga; E Garattini
Journal:  Biochem J       Date:  1994-02-15       Impact factor: 3.857

7.  The housekeeping gene xanthine oxidoreductase is necessary for milk fat droplet enveloping and secretion: gene sharing in the lactating mammary gland.

Authors:  Claudia Vorbach; Alistair Scriven; Mario R Capecchi
Journal:  Genes Dev       Date:  2002-12-15       Impact factor: 11.361

8.  Tissue- and cell-specific expression of mouse xanthine oxidoreductase gene in vivo: regulation by bacterial lipopolysaccharide.

Authors:  M Kurosaki; M Li Calzi; E Scanziani; E Garattini; M Terao
Journal:  Biochem J       Date:  1995-02-15       Impact factor: 3.857

9.  Isolation and characterization of the human aldehyde oxidase gene: conservation of intron/exon boundaries with the xanthine oxidoreductase gene indicates a common origin.

Authors:  M Terao; M Kurosaki; S Demontis; S Zanotta; E Garattini
Journal:  Biochem J       Date:  1998-06-01       Impact factor: 3.857

10.  Pyrido[3,4-d]pyrimidin-4(3H)-one metabolism mediated by aldehyde oxidase is blocked by C2-substitution.

Authors:  Angela Hayes; N Yi Mok; Manjuan Liu; Ching Thai; Alan T Henley; Butrus Atrash; Rachel M Lanigan; Jemmy Sejberg; Yann-Vaï Le Bihan; Vassilios Bavetsias; Julian Blagg; Florence I Raynaud
Journal:  Xenobiotica       Date:  2016-10-26       Impact factor: 1.908
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