Literature DB >> 23500952

Recent advances in marine drug research.

Saradavey Vinothkumar1, P S Parameswaran.   

Abstract

Structures and properties of promising marine anti-cancer, anti-inflammation and anti-infectious (HIV, HSV, malaria, leishmania) compounds reported during 2008-2011 are discussed. Wherever possible, attempts have also been made to highlight their possible biogenesis or structure-activity relationships (SAR). Since the stress is on identifying and short-listing potential drug molecules, this review is restricted to only those compounds exhibiting promising in vitro activity, the arbitrary cut off being IC50<15 μM, reported during the above period.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Alkaloid; Anti-cancer; Anti-infectious; Anti-inflammation; Depsipeptide; Lipopeptide; Sponge

Mesh:

Substances:

Year:  2013        PMID: 23500952     DOI: 10.1016/j.biotechadv.2013.02.006

Source DB:  PubMed          Journal:  Biotechnol Adv        ISSN: 0734-9750            Impact factor:   14.227


  24 in total

1.  Pteridic acids C-G spirocyclic polyketides from the marine-derived Streptomyces sp. SCSGAA 0027.

Authors:  Xu-Hua Nong; Xiao-Yi Wei; Shu-Hua Qi
Journal:  J Antibiot (Tokyo)       Date:  2017-09-27       Impact factor: 2.649

Review 2.  Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.

Authors:  Maria Letizia Ciavatta; Florence Lefranc; Marianna Carbone; Ernesto Mollo; Margherita Gavagnin; Tania Betancourt; Ramesh Dasari; Alexander Kornienko; Robert Kiss
Journal:  Med Res Rev       Date:  2016-12-07       Impact factor: 12.944

Review 3.  Bioactive Compounds from Marine Heterobranchs.

Authors:  Conxita Avila; Carlos Angulo-Preckler
Journal:  Mar Drugs       Date:  2020-12-21       Impact factor: 5.118

4.  Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of Patched and increase chemotherapy efficiency on melanoma cells.

Authors:  Laura Fiorini; Marie-Aude Tribalat; Lucy Sauvard; Julie Cazareth; Enzo Lalli; Isabelle Broutin; Olivier P Thomas; Isabelle Mus-Veteau
Journal:  Oncotarget       Date:  2015-09-08

5.  Metabolomic tools for secondary metabolite discovery from marine microbial symbionts.

Authors:  Lynsey Macintyre; Tong Zhang; Christina Viegelmann; Ignacio Juarez Martinez; Cheng Cheng; Catherine Dowdells; Usama Ramadam Abdelmohsen; Christine Gernert; Ute Hentschel; RuAngelie Edrada-Ebel
Journal:  Mar Drugs       Date:  2014-06-05       Impact factor: 5.118

6.  The marine metabolite SZ-685C induces apoptosis in primary human nonfunctioning pituitary adenoma cells by inhibition of the Akt pathway in vitro.

Authors:  Xin Wang; Ting Tan; Zhi-Gang Mao; Ni Lei; Zong-Ming Wang; Bin Hu; Zhi-Yong Chen; Zhi-Gang She; Yong-Hong Zhu; Hai-Jun Wang
Journal:  Mar Drugs       Date:  2015-03-23       Impact factor: 5.118

7.  Anti-inflammatory effects of secondary metabolites of marine Pseudomonas sp. in human neutrophils are through inhibiting P38 MAPK, JNK, and calcium pathways.

Authors:  Shun-Chin Yang; Ping-Jyun Sung; Chwan-Fwu Lin; Jimmy Kuo; Chun-Yu Chen; Tsong-Long Hwang
Journal:  PLoS One       Date:  2014-12-04       Impact factor: 3.240

Review 8.  Marine low molecular weight natural products as potential cancer preventive compounds.

Authors:  Valentin A Stonik; Sergey N Fedorov
Journal:  Mar Drugs       Date:  2014-01-27       Impact factor: 5.118

Review 9.  Advances in the study of the structures and bioactivities of metabolites isolated from mangrove-derived fungi in the South China Sea.

Authors:  Xin Wang; Zhi-Gang Mao; Bing-Bing Song; Chun-Hua Chen; Wei-Wei Xiao; Bin Hu; Ji-Wen Wang; Xiao-Bing Jiang; Yong-Hong Zhu; Hai-Jun Wang
Journal:  Mar Drugs       Date:  2013-09-30       Impact factor: 5.118

Review 10.  Marine Invertebrate Metabolites with Anticancer Activities: Solutions to the "Supply Problem".

Authors:  Nelson G M Gomes; Ramesh Dasari; Sunena Chandra; Robert Kiss; Alexander Kornienko
Journal:  Mar Drugs       Date:  2016-05-21       Impact factor: 5.118

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