Literature DB >> 2350061

Physiology in fractal dimensions: error tolerance.

B J West1.   

Abstract

The natural variability in physiological form and function is herein related to the geometric concept of a fractal. The average dimensions of the branches in the tracheobronchial tree, long thought to be exponential, are shown to be an inverse power law of the generation number modulated by a harmonic variation. A similar functional form is found for the power spectrum of the QRS-complex of the healthy human heart. These results follow from the assumption that the bronchial tree and the cardiac conduction system are fractal forms. The fractal concept provides a mechanism for the morphogenesis of complex structures which are more stable than those generated by classical scaling (i.e., they are more error tolerant).

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Year:  1990        PMID: 2350061     DOI: 10.1007/bf02368426

Source DB:  PubMed          Journal:  Ann Biomed Eng        ISSN: 0090-6964            Impact factor:   3.934


  4 in total

1.  Architecture of the human lung. Use of quantitative methods establishes fundamental relations between size and number of lung structures.

Authors:  E R WEIBEL; D M GOMEZ
Journal:  Science       Date:  1962-08-24       Impact factor: 47.728

2.  Beyond the principle of similitude: renormalization in the bronchial tree.

Authors:  B J West; V Bhargava; A L Goldberger
Journal:  J Appl Physiol (1985)       Date:  1986-03

3.  On a mechanism of cardiac electrical stability. The fractal hypothesis.

Authors:  A L Goldberger; V Bhargava; B J West; A J Mandell
Journal:  Biophys J       Date:  1985-09       Impact factor: 4.033

4.  Fractals in physiology and medicine.

Authors:  A L Goldberger; B J West
Journal:  Yale J Biol Med       Date:  1987 Sep-Oct
  4 in total
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Journal:  Integr Physiol Behav Sci       Date:  1998 Jan-Mar

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Authors:  J H Bates; G N Maksym; D Navajas; B Suki
Journal:  Ann Biomed Eng       Date:  1994 Nov-Dec       Impact factor: 3.934

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