| Literature DB >> 23499954 |
Juan M Sonego1, Adriana M Cirigliano, Gabriela M Cabrera, Gerardo Burton, Adriana S Veleiro.
Abstract
Six analogues of salpichrolides with a simplified side chain (6-11) were synthesized using a new methodology to obtain steroids with an aromatic D-ring. The key step was the elimination of HBr in a vicinal dibromo D-homosteroid by treatment with 1,4-diazabicyclo[2.2.2]octane (DABCO). All new compounds were completely characterized by 2D NMR techniques and tested on two fungal pathogenic species, Fusarium virguliforme and Fusarium solani.Entities:
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Year: 2013 PMID： 23499954 DOI： 10.1016/j.steroids.2013.02.003
Source DB: PubMed Journal: Steroids ISSN： 0039-128X Impact factor: 2.668