Literature DB >> 23494534

Hypothesis: local dNTP depletion as the cause of microsatellite repeat instability during replication (comment on DOI 10.1002/bies.201200128).

Michael Leffak1.   

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Year:  2013        PMID: 23494534      PMCID: PMC4034735          DOI: 10.1002/bies.201300026

Source DB:  PubMed          Journal:  Bioessays        ISSN: 0265-9247            Impact factor:   4.345


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  6 in total

1.  Trinucleotide repeats that expand in human disease form hairpin structures in vitro.

Authors:  A M Gacy; G Goellner; N Juranić; S Macura; C T McMurray
Journal:  Cell       Date:  1995-05-19       Impact factor: 41.582

2.  Oligodeoxynucleotide binding to (CTG) · (CAG) microsatellite repeats inhibits replication fork stalling, hairpin formation, and genome instability.

Authors:  Guoqi Liu; Xiaomi Chen; Michael Leffak
Journal:  Mol Cell Biol       Date:  2012-11-19       Impact factor: 4.272

3.  Nucleotide deficiency promotes genomic instability in early stages of cancer development.

Authors:  Assaf C Bester; Maayan Roniger; Yifat S Oren; Michael M Im; Dan Sarni; Malka Chaoat; Aaron Bensimon; Gideon Zamir; Donna S Shewach; Batsheva Kerem
Journal:  Cell       Date:  2011-04-29       Impact factor: 41.582

4.  Inhibition of DNA synthesis facilitates expansion of low-complexity repeats: is strand slippage stimulated by transient local depletion of specific dNTPs?

Authors:  Andrei Kuzminov
Journal:  Bioessays       Date:  2013-01-15       Impact factor: 4.345

Review 5.  Identification of early replicating fragile sites that contribute to genome instability.

Authors:  Jacqueline H Barlow; Robert B Faryabi; Elsa Callén; Nancy Wong; Amy Malhowski; Hua Tang Chen; Gustavo Gutierrez-Cruz; Hong-Wei Sun; Peter McKinnon; George Wright; Rafael Casellas; Davide F Robbiani; Louis Staudt; Oscar Fernandez-Capetillo; André Nussenzweig
Journal:  Cell       Date:  2013-01-24       Impact factor: 41.582

6.  Initiation of genome instability and preneoplastic processes through loss of Fhit expression.

Authors:  Joshua C Saldivar; Satoshi Miuma; Jessica Bene; Seyed Ali Hosseini; Hidetaka Shibata; Jin Sun; Linda J Wheeler; Christopher K Mathews; Kay Huebner
Journal:  PLoS Genet       Date:  2012-11-29       Impact factor: 5.917

  6 in total
  1 in total

Review 1.  A Critical Balance: dNTPs and the Maintenance of Genome Stability.

Authors:  Chen-Chun Pai; Stephen E Kearsey
Journal:  Genes (Basel)       Date:  2017-01-31       Impact factor: 4.096

  1 in total

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