BACKGROUND: The macroscopic structure of bone has been traditionally studied through x-ray radiography or x-ray tomography. However, the resolution limits of these techniques do not enable the reconstruction of the composite bone architecture at the nanometer level. Compared with histomorphometry, x-ray micro-CT has shown its efficiency in providing nondestructive and rapid 3D images and measurements on bone microstructure. Micro-CT higher resolution has been achieved with synchrotron radiation-based computed microtomography (SRμCT). PURPOSE: The aim of this study was a histological and SRμCT analysis of 2 porous titanium implants. MATERIALS AND METHODS: Two direct laser metal forming titanium implants were inserted in the posterior maxilla of a patient and retrieved after 2 months. One of these implants was treated to obtain thin ground sections, whereas the other underwent a SRμCT evaluation. RESULTS: The histological results, showing that the implant surface presented superficial debris and particle inclusions in the surrounding tissue close to the bone area, were confirmed by micro-CT investigations. CONCLUSIONS: SRμCT allowed high resolution with good sample penetration and depth of focus and an evaluation of the relative arrangement of structures that cannot be determined by 2D imaging.
BACKGROUND: The macroscopic structure of bone has been traditionally studied through x-ray radiography or x-ray tomography. However, the resolution limits of these techniques do not enable the reconstruction of the composite bone architecture at the nanometer level. Compared with histomorphometry, x-ray micro-CT has shown its efficiency in providing nondestructive and rapid 3D images and measurements on bone microstructure. Micro-CT higher resolution has been achieved with synchrotron radiation-based computed microtomography (SRμCT). PURPOSE: The aim of this study was a histological and SRμCT analysis of 2 porous titanium implants. MATERIALS AND METHODS: Two direct laser metal forming titanium implants were inserted in the posterior maxilla of a patient and retrieved after 2 months. One of these implants was treated to obtain thin ground sections, whereas the other underwent a SRμCT evaluation. RESULTS: The histological results, showing that the implant surface presented superficial debris and particle inclusions in the surrounding tissue close to the bone area, were confirmed by micro-CT investigations. CONCLUSIONS: SRμCT allowed high resolution with good sample penetration and depth of focus and an evaluation of the relative arrangement of structures that cannot be determined by 2D imaging.
Authors: James Tedesco; Bryan E J Lee; Alex Y W Lin; Dakota M Binkley; Kathleen H Delaney; Jacek M Kwiecien; Kathryn Grandfield Journal: Int J Dent Date: 2017-11-19
Authors: Carlo Mangano; Francesco Guido Mangano; Jamil Awad Shibli; Leandro Amadeu Roth; Gianmaria d' Addazio; Adriano Piattelli; Giovanna Iezzi Journal: Int J Environ Res Public Health Date: 2018-07-30 Impact factor: 3.390
Authors: Carlo Mangano; Alessandra Giuliani; Ilaria De Tullio; Mario Raspanti; Adriano Piattelli; Giovanna Iezzi Journal: Front Bioeng Biotechnol Date: 2021-04-15