Literature DB >> 2349198

The cardiovascular effects of beta adrenergic agonist drugs administered by nebulisation.

A Flatt1, J Crane, G Purdie, T Kwong, R Beasley, C Burgess.   

Abstract

The cardiovascular effects of equal doses (5 mg) of nebulised fenoterol, salbutamol and terbutaline were compared in 12 healthy individuals in a double-blind, placebo-controlled study. Measurements of heart rate, blood pressure, systolic time intervals, QTc interval and T-wave amplitude were made at baseline and at 15, 30, 45, 60 and 90 minutes after nebulisation. Fenoterol caused significantly greater chronotropic electrocardiographic and inotropic effects than either salbutamol or terbutaline. The peak effects after terbutaline occurred later than those after fenoterol or salbutamol.

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Year:  1990        PMID: 2349198      PMCID: PMC2429517          DOI: 10.1136/pgmj.66.772.98

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


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  6 in total

1.  The cardiovascular effects of beta adrenergic agonist drugs administered by nebulization.

Authors:  J A Hall
Journal:  Postgrad Med J       Date:  1991-02       Impact factor: 2.401

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6.  Short-term safety and tolerability of double-dose salmeterol/fluticasone propionate in adult asthmatic patients.

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