Literature DB >> 23490599

Addition of exenatide or sitagliptin to insulin in new onset type 1 diabetes: a randomized, open label study.

K V S Hari Kumar1, Altamash Shaikh, Pitambar Prusty.   

Abstract

Incretin based therapies are known to have pleotropic benefits in type 2 diabetes but have not been studied in new onset type 1 diabetes. In this randomized, open label study, we investigated the effect of the addition of exenatide or sitagliptin to insulin in patients with new onset type 1 diabetes. Our data suggest that the addition of exenatide and sitagliptin decreases insulin requirements without increasing endogenous insulin production and hypoglycemic events.
Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

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Year:  2013        PMID: 23490599     DOI: 10.1016/j.diabres.2013.01.020

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN: 0168-8227            Impact factor:   5.602


  30 in total

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Review 4.  Glucose-Lowering Therapy beyond Insulin in Type 1 Diabetes: A Narrative Review on Existing Evidence from Randomized Controlled Trials and Clinical Perspective.

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6.  Combining MK626, a novel DPP-4 inhibitor, and low-dose monoclonal CD3 antibody for stable remission of new-onset diabetes in mice.

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Journal:  PLoS One       Date:  2014-09-30       Impact factor: 3.240

7.  One year remission of type 1 diabetes mellitus in a patient treated with sitagliptin.

Authors:  Marcos M Lima-Martínez; Ernesto Guerra-Alcalá; Miguel Contreras; José Nastasi; Janelle A Noble; Constantin Polychronakos
Journal:  Endocrinol Diabetes Metab Case Rep       Date:  2014-09-01

Review 8.  Obesity in Patients with Type 1 Diabetes: Links, Risks and Management Challenges.

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Journal:  Diabetes Metab Syndr Obes       Date:  2021-06-21       Impact factor: 3.168

Review 9.  Type 1 diabetes and cardiovascular disease.

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10.  Preliminary study characterizing the use of sitagliptin for glycemic control in healthy Beagle dogs with normal gluco-homeostasis.

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Journal:  J Vet Med Sci       Date:  2014-06-16       Impact factor: 1.267

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