Literature DB >> 23487823

Traumatic brain injury in adults.

Angelos G Kolias1, Mathew R Guilfoyle, Adel Helmy, Judith Allanson, Peter J Hutchinson.   

Abstract

Traumatic brain injury (TBI) remains a major public health problem. This review aims to present the principles upon which modern TBI management should be based. The early management phase aims to achieve haemodynamic stability, limit secondary insults (eg hypotension, hypoxia), obtain accurate neurological assessment and appropriately select patients for further investigation. Since 2003, the mainstay of risk stratification in the UK emergency departments has been a system of triage based on clinical assessment, which then dictates the need for a CT scan of the head. For patients with acute subdural or extradural haematomas, time from clinical deterioration to operation should be kept to a minimum, as it can affect their outcome. In addition, it is increasingly recognised that patients with severe and moderate TBI should be managed in neuroscience centres, regardless of the need for neurosurgical intervention. The monitoring and treatment of raised intracranial pressure is paramount for maintaining cerebral blood supply and oxygen delivery in patients with severe TBI. Decompressive craniectomy and therapeutic hypothermia are the subject of ongoing international multi-centre randomised trials. TBI is associated with a number of complications, some of which require specialist referral. Patients with post-concussion syndrome can be helped by supportive management in the context of a multi-disciplinary neurotrauma clinic and by patient support groups. Specialist neurorehabilitation after TBI is important for improving outcome.

Entities:  

Keywords:  Neurosurgery; Traumatic Brain Injury

Mesh:

Year:  2013        PMID: 23487823     DOI: 10.1136/practneurol-2012-000268

Source DB:  PubMed          Journal:  Pract Neurol        ISSN: 1474-7758


  21 in total

Review 1.  Post-traumatic headaches: an epidemiological overview.

Authors:  F D'Onofrio; A Russo; F Conte; G Casucci; A Tessitore; G Tedeschi
Journal:  Neurol Sci       Date:  2014-05       Impact factor: 3.307

2.  Relationship of vascular wall tension and autoregulation following traumatic brain injury.

Authors:  Georgios V Varsos; Karol P Budohoski; Angelos G Kolias; Xiuyun Liu; Peter Smielewski; Vassilis G Varsos; Peter J Hutchinson; John D Pickard; Marek Czosnyka
Journal:  Neurocrit Care       Date:  2014-10       Impact factor: 3.210

Review 3.  Glucose metabolism following human traumatic brain injury: methods of assessment and pathophysiological findings.

Authors:  Ibrahim Jalloh; Keri L H Carpenter; Adel Helmy; T Adrian Carpenter; David K Menon; Peter J Hutchinson
Journal:  Metab Brain Dis       Date:  2014-11-21       Impact factor: 3.584

Review 4.  Concussion is confusing us all.

Authors:  David J Sharp; Peter O Jenkins
Journal:  Pract Neurol       Date:  2015-06

Review 5.  Systemic, local, and imaging biomarkers of brain injury: more needed, and better use of those already established?

Authors:  Keri L H Carpenter; Marek Czosnyka; Ibrahim Jalloh; Virginia F J Newcombe; Adel Helmy; Richard J Shannon; Karol P Budohoski; Angelos G Kolias; Peter J Kirkpatrick; Thomas Adrian Carpenter; David K Menon; Peter J Hutchinson
Journal:  Front Neurol       Date:  2015-02-18       Impact factor: 4.003

6.  Emergency care of traumatic brain injuries in Pakistan: a multicenter study.

Authors:  Junaid Bhatti; Kent Stevens; Muhammad Mir; Adnan A Hyder; Junaid Razzak
Journal:  BMC Emerg Med       Date:  2015-12-11

7.  Notch-1 signaling regulates microglia activation via NF-κB pathway after hypoxic exposure in vivo and in vitro.

Authors:  Linli Yao; Enci Mary Kan; Charanjit Kaur; S Thameem Dheen; Aijun Hao; Jia Lu; Eng-Ang Ling
Journal:  PLoS One       Date:  2013-11-06       Impact factor: 3.240

Review 8.  (13)C-labelled microdialysis studies of cerebral metabolism in TBI patients.

Authors:  Keri L H Carpenter; Ibrahim Jalloh; Clare N Gallagher; Peter Grice; Duncan J Howe; Andrew Mason; Ivan Timofeev; Adel Helmy; Michael P Murphy; David K Menon; Peter J Kirkpatrick; T Adrian Carpenter; Garnette R Sutherland; John D Pickard; Peter J Hutchinson
Journal:  Eur J Pharm Sci       Date:  2013-12-20       Impact factor: 4.384

Review 9.  Decompressive craniectomy following traumatic brain injury: developing the evidence base.

Authors:  Angelos G Kolias; Hadie Adams; Ivan Timofeev; Marek Czosnyka; Elizabeth A Corteen; John D Pickard; Carole Turner; Barbara A Gregson; Peter J Kirkpatrick; Gordon D Murray; David K Menon; Peter J Hutchinson
Journal:  Br J Neurosurg       Date:  2016-03-14       Impact factor: 1.596

10.  Moderate traumatic brain injury, acute phase course and deviations in physiological variables: an observational study.

Authors:  Stine B Lund; Kari H Gjeilo; Kent G Moen; Kari Schirmer-Mikalsen; Toril Skandsen; Anne Vik
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2016-05-23       Impact factor: 2.953

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