Literature DB >> 23486886

Ophelia syndrome with metabotropic glutamate receptor 5 antibodies in CSF.

Arimin Mat1, Hugh Adler, Aine Merwick, Geoff Chadwick, Giuseppe Gullo, Josep O Dalmau, Niall Tubridy.   

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Year:  2013        PMID： 23486886      PMCID： PMC3656459          DOI： 10.1212/WNL.0b013e31828ab325

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


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  5 in total

1.  Paraneoplastic acute diffuse encephalitis revealing Hodgkin's disease.

Authors:  O Epaulard; S Courby; P Pavese; S Grand; M Laramas; L Molina; J P Brion; P-E Colle; J J Sotto
Journal:  Leuk Lymphoma       Date:  2004-12

2.  Antibodies to metabotropic glutamate receptor 5 in the Ophelia syndrome.

Authors:  E Lancaster; E Martinez-Hernandez; M J Titulaer; M Boulos; S Weaver; J-C Antoine; E Liebers; C Kornblum; C G Bien; J Honnorat; S Wong; J Xu; A Contractor; R Balice-Gordon; J Dalmau
Journal:  Neurology       Date:  2011-10-19       Impact factor: 9.910

3.  Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP.

Authors:  Y M Lu; Z Jia; C Janus; J T Henderson; R Gerlai; J M Wojtowicz; J C Roder
Journal:  J Neurosci       Date:  1997-07-01       Impact factor: 6.167

4.  The Ophelia syndrome: memory loss in Hodgkin's disease.

Authors:  I Carr
Journal:  Lancet       Date:  1982-04-10       Impact factor: 79.321

5.  Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients.

Authors:  S H Gultekin; M R Rosenfeld; R Voltz; J Eichen; J B Posner; J Dalmau
Journal:  Brain       Date:  2000-07       Impact factor: 13.501
  5 in total
  15 in total

Review 1.  Neuronal surface antibody-mediated autoimmune encephalitis.

Authors:  Jenny J Linnoila; Myrna R Rosenfeld; Josep Dalmau
Journal:  Semin Neurol       Date:  2014-11-04       Impact factor: 3.420

2.  Encephalitis with mGluR5 antibodies: Symptoms and antibody effects.

Authors:  Marianna Spatola; Lidia Sabater; Jesús Planagumà; Eugenia Martínez-Hernandez; Thaís Armangué; Harald Prüss; Takahiro Iizuka; Ruben L Caparó Oblitas; Jean-Christophe Antoine; Richard Li; Nicholas Heaney; Niall Tubridy; Elvira Munteis Olivas; Myrna R Rosenfeld; Francesc Graus; Josep Dalmau
Journal:  Neurology       Date:  2018-04-27       Impact factor: 9.910

Review 3.  Neuronal central nervous system syndromes probably mediated by autoantibodies.

Authors:  Aude Chefdeville; Jérôme Honnorat; Christiane S Hampe; Virginie Desestret
Journal:  Eur J Neurosci       Date:  2016-03-28       Impact factor: 3.386

Review 4.  Autoantibodies as Endogenous Modulators of GPCR Signaling.

Authors:  Meredith A Skiba; Andrew C Kruse
Journal:  Trends Pharmacol Sci       Date:  2020-12-24       Impact factor: 14.819

Review 5.  Autoantibodies to Synaptic Receptors and Neuronal Cell Surface Proteins in Autoimmune Diseases of the Central Nervous System.

Authors:  Josep Dalmau; Christian Geis; Francesc Graus
Journal:  Physiol Rev       Date:  2017-04       Impact factor: 37.312

Review 6.  Autoimmune encephalitis as differential diagnosis of infectious encephalitis.

Authors:  Thaís Armangue; Frank Leypoldt; Josep Dalmau
Journal:  Curr Opin Neurol       Date:  2014-06       Impact factor: 5.710

Review 7.  Autoimmune encephalopathies.

Authors:  Frank Leypoldt; Thaís Armangue; Josep Dalmau
Journal:  Ann N Y Acad Sci       Date:  2014-10-14       Impact factor: 5.691

Review 8.  Recognizing Autoimmune-Mediated Encephalitis in the Differential Diagnosis of Limbic Disorders.

Authors:  A J da Rocha; R H Nunes; A C M Maia; L L F do Amaral
Journal:  AJNR Am J Neuroradiol       Date:  2015-09-17       Impact factor: 3.825

Review 9.  Glutamate receptor antibodies in neurological diseases: anti-AMPA-GluR3 antibodies, anti-NMDA-NR1 antibodies, anti-NMDA-NR2A/B antibodies, anti-mGluR1 antibodies or anti-mGluR5 antibodies are present in subpopulations of patients with either: epilepsy, encephalitis, cerebellar ataxia, systemic lupus erythematosus (SLE) and neuropsychiatric SLE, Sjogren's syndrome, schizophrenia, mania or stroke. These autoimmune anti-glutamate receptor antibodies can bind neurons in few brain regions, activate glutamate receptors, decrease glutamate receptor's expression, impair glutamate-induced signaling and function, activate blood brain barrier endothelial cells, kill neurons, damage the brain, induce behavioral/psychiatric/cognitive abnormalities and ataxia in animal models, and can be removed or silenced in some patients by immunotherapy.

Authors:  Mia Levite
Journal:  J Neural Transm (Vienna)       Date:  2014-08-01       Impact factor: 3.575

Review 10.  Paraneoplastic neurological syndromes in Hodgkin and non-Hodgkin lymphomas.

Authors:  Francesc Graus; Helena Ariño; Josep Dalmau
Journal:  Blood       Date:  2014-04-04       Impact factor: 22.113
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