Literature DB >> 23486861

Iodine-mediated intramolecular amination of ketones: the synthesis of 2-acylindoles and 2-acylindolines by tuning N-protecting groups.

Wen-Chao Gao1, Shan Jiang, Ruo-Lin Wang, Chi Zhang.   

Abstract

A general method for constructing both 2-acylindoles and 2-acylindolines via I2-mediated intramolecular C-N bond formation is presented, and the selective formation of either 2-acylindoles or 2-acylindolines just depends on the nitrogen protecting groups used in the same substrate skeletons.

Entities:  

Year:  2013        PMID： 23486861     DOI： 10.1039/c3cc40797g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Brönsted acid-catalyzed one-pot synthesis of indoles from o-aminobenzyl alcohols and furans.

Authors:  Alexey Kuznetsov; Anton Makarov; Aleksandr E Rubtsov; Alexander V Butin; Vladimir Gevorgyan
Journal:  J Org Chem       Date:  2013-11-20       Impact factor: 4.354

2.  I2-catalyzed intramolecular oxidative amination of C(sp3)-H bond: efficient access to 3-acylimidazo[1,2-a]pyridines under neat condition.

Authors:  Lilan Huang; Wenqing Yin; Jian Wang; Chunfang Gan; Yanmin Huang; Chusheng Huang; Yimiao He
Journal:  RSC Adv       Date:  2019-01-18       Impact factor: 4.036

3.  Design, Synthesis and Molecular Docking Study of Novel 3-Phenyl-β-Alanine-Based Oxadiazole Analogues as Potent Carbonic Anhydrase II Inhibitors.

Authors:  Kashif Rafiq; Najeeb Ur Rehman; Sobia Ahsan Halim; Majid Khan; Ajmal Khan; Ahmed Al-Harrasi
Journal:  Molecules       Date:  2022-01-26       Impact factor: 4.411
  3 in total

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