Literature DB >> 23486714

Comparison of the Abbott m2000 RealTime CT assay and the Cepheid GeneXpert CT/NG assay to the Roche Amplicor CT assay for detection of Chlamydia trachomatis in ocular samples from Tanzania.

Laura Dize1, Sheila West, James A Williams, Barbara Van Der Pol, Thomas C Quinn, Charlotte A Gaydos.   

Abstract

The GeneXpert CT/NG assay (GeneXpert) and the Abbott m2000 RealTime CT (m2000) assay were compared to Amplicor for detecting ocular Chlamydia trachomatis. Discordant specimens were tested by the Aptima CT assay. The m2000 assay sensitivity was 100% (95% confidence interval [CI], 90% to 100%), and specificity was 98.46% (95% CI, 95.2% to 99.2%); GeneXpert sensitivity was 100% (95% CI, 90% to 100%), and specificity was 100% (95% CI, 98.1% to 100%). The m2000 and GeneXpert assays appear to perform as well as the Amplicor assay.

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Year:  2013        PMID： 23486714      PMCID： PMC3647953          DOI： 10.1128/JCM.00519-13

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  8 in total

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Authors:  Craig W See; Wondu Alemayehu; Muluken Melese; Zhaoxia Zhou; Travis C Porco; Stephen Shiboski; Bruce D Gaynor; John Eng; Jeremy D Keenan; Thomas M Lietman
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-08-03       Impact factor: 4.799

3.  Strategies for control of trachoma: observational study with quantitative PCR.

Authors:  Anthony W Solomon; Martin J Holland; Matthew J Burton; Sheila K West; Neal D E Alexander; Aura Aguirre; Patrick A Massae; Harran Mkocha; Beatriz Muñoz; Gordon J Johnson; Rosanna W Peeling; Robin L Bailey; Allen Foster; David C W Mabey
Journal:  Lancet       Date:  2003-07-19       Impact factor: 79.321

4.  Detection of Chlamydia trachomatis ocular infection in trachoma-endemic communities by rRNA amplification.

Authors:  Jon L Yang; Kevin C Hong; Julius Schachter; Jeanne Moncada; Takele Lekew; Jenafir I House; Zhaoxia Zhou; Melissa D Neuwelt; Tina Rutar; Colleen Halfpenny; Neelima Shah; John P Whitcher; Thomas M Lietman
Journal:  Invest Ophthalmol Vis Sci       Date:  2008-08-08       Impact factor: 4.799

5.  Effect of a single mass antibiotic distribution on the prevalence of infectious trachoma.

Authors:  Jaya D Chidambaram; Wondu Alemayehu; Muluken Melese; Takele Lakew; Elizabeth Yi; Jenafir House; Vicky Cevallos; Zhaoxia Zhou; Kathryn Maxey; David C Lee; Brett L Shapiro; Muthiah Srinivasan; Travis Porco; John P Whitcher; Bruce D Gaynor; Thomas M Lietman
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6.  Risk factors for ocular infection with Chlamydia trachomatis in children 6 months following mass treatment in Tanzania.

Authors:  Luis Carlos Cajas-Monson; Harran Mkocha; Beatriz Muñoz; Thomas C Quinn; Charlotte A Gaydos; Sheila K West
Journal:  PLoS Negl Trop Dis       Date:  2011-03-15

7.  Trachoma prevalence and associated risk factors in the gambia and Tanzania: baseline results of a cluster randomised controlled trial.

Authors:  Emma M Harding-Esch; Tansy Edwards; Harran Mkocha; Beatriz Munoz; Martin J Holland; Sarah E Burr; Ansumana Sillah; Charlotte A Gaydos; Dianne Stare; David C W Mabey; Robin L Bailey; Sheila K West
Journal:  PLoS Negl Trop Dis       Date:  2010-11-02

Review 8.  Epidemiology and control of trachoma: systematic review.

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Journal:  Trop Med Int Health       Date:  2010-04-04       Impact factor: 2.622
  8 in total
  19 in total

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Journal:  Sex Transm Infect       Date:  2015-04-01       Impact factor: 3.519

2.  Review of use of a new rapid real-time PCR, the Cepheid GeneXpert® (Xpert) CT/NG assay, for Chlamydia trachomatis and Neisseria gonorrhoeae: results for patients while in a clinical setting.

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Journal:  Expert Rev Mol Diagn       Date:  2014-01-23       Impact factor: 5.225

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5.  Meta-analysis of the Cepheid Xpert® CT/NG assay for extragenital detection of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections.

Authors:  Claire C Bristow; Sheldon R Morris; Susan J Little; Sanjay R Mehta; Jeffrey D Klausner
Journal:  Sex Health       Date:  2019-08       Impact factor: 2.706

Review 6.  Ocular Chlamydia trachomatis infection: elimination with mass drug administration.

Authors:  Meraf A Wolle; Sheila K West
Journal:  Expert Rev Anti Infect Ther       Date:  2019-02-18       Impact factor: 5.091

7.  Pooling ocular swab specimens from Tanzania for testing by Roche Amplicor and Aptima Combo 2 assays for the detection of Chlamydia trachomatis: accuracy and cost-savings.

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Authors:  Claire C Bristow; Mark R McGrath; Adam C Cohen; Laura J Anderson; Kristie K Gordon; Jeffrey D Klausner
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9.  Precision of the Abbott RealTime Assay in the Detection of Ocular Chlamydia trachomatis in a Trachoma-Endemic Area of Ethiopia.

Authors:  Kieran S O'Brien; Ambahun Chernet; Jeanne Moncada; Julius Schachter; Paul M Emerson; Scott D Nash; Melsew Chanyalew; Zerihun Tadesse; Zhaoxia Zhou; Charles E McCulloch; Thomas M Lietman; Jeremy D Keenan
Journal:  Am J Trop Med Hyg       Date:  2020-05-07       Impact factor: 2.345

10.  Field evaluation of the Cepheid GeneXpert Chlamydia trachomatis assay for detection of infection in a trachoma endemic community in Tanzania.

Authors:  Alexander Jenson; Laura Dize; Harran Mkocha; Beatriz Munoz; Jennifer Lee; Charlotte Gaydos; Thomas Quinn; Sheila K West
Journal:  PLoS Negl Trop Dis       Date:  2013-07-04
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