Literature DB >> 23485434

A perfect time to harness advanced molecular technologies to explore the fundamental biology of Toxocara species.

Robin B Gasser1.   

Abstract

Toxocarosis is of major canine health and socioeconomic importance worldwide. Although many studies have given insights into toxocarosis, to date, there has been limited exploration of the molecular biology, biochemistry, genetics, epidemiology and ecology of Toxocara species as well as parasite-host interactions using '-omic' technologies. The present article gives a background on Toxocara species and toxocarosis, describes molecular tools for specific identification and genetic analysis, and provides a prospective view of the benefits that advanced molecular technologies will have towards better understanding the parasites and disease. Tackling key biological questions employing a 'systems biology' approach should lead to new and improved strategies for the treatment, diagnosis and control of toxocarosis.
Copyright © 2013. Published by Elsevier B.V.

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Year:  2012        PMID: 23485434     DOI: 10.1016/j.vetpar.2012.12.031

Source DB:  PubMed          Journal:  Vet Parasitol        ISSN: 0304-4017            Impact factor:   2.738


  14 in total

1.  Assessment of the efficacy of thymol against Toxocara vitulorum in experimentally infected rats.

Authors:  Olfat Shehata; Shawky M Aboelhadid; Waleed M Arafa; Usama K Moawad; Khaled H Hussien; Mona Ibrahim Ali; Saeed El-Ashram; Samah Sayed Abdel Gawad; Sahar Abdel Aleem Abdel-Aziz
Journal:  J Parasit Dis       Date:  2022-01-30

2.  Genetic blueprint of the zoonotic pathogen Toxocara canis.

Authors:  Xing-Quan Zhu; Pasi K Korhonen; Huimin Cai; Neil D Young; Peter Nejsum; Georg von Samson-Himmelstjerna; Peter R Boag; Patrick Tan; Qiye Li; Jiumeng Min; Yulan Yang; Xiuhua Wang; Xiaodong Fang; Ross S Hall; Andreas Hofmann; Paul W Sternberg; Aaron R Jex; Robin B Gasser
Journal:  Nat Commun       Date:  2015-02-04       Impact factor: 14.919

3.  MicroRNAs of Toxocara canis and their predicted functional roles.

Authors:  Guangxu Ma; Yongfang Luo; Honghong Zhu; Yongli Luo; Pasi K Korhonen; Neil D Young; Robin B Gasser; Rongqiong Zhou
Journal:  Parasit Vectors       Date:  2016-04-23       Impact factor: 3.876

4.  Proof of concept of faecal egg nematode counting as a practical means of veterinary engagement with planned livestock health management in a lower income country.

Authors:  Eithne Leahy; Barend Bronsvoort; Luke Gamble; Andrew Gibson; Henderson Kaponda; Dagmar Mayer; Stella Mazeri; Kate Shervell; Neil Sargison
Journal:  Ir Vet J       Date:  2017-06-02       Impact factor: 2.146

Review 5.  Impact of gastrointestinal parasitic nematodes of sheep, and the role of advanced molecular tools for exploring epidemiology and drug resistance - an Australian perspective.

Authors:  Florian Roeber; Aaron R Jex; Robin B Gasser
Journal:  Parasit Vectors       Date:  2013-05-27       Impact factor: 3.876

6.  Toxocara canis: molecular basis of immune recognition and evasion.

Authors:  Rick M Maizels
Journal:  Vet Parasitol       Date:  2012-12-20       Impact factor: 2.738

Review 7.  Rendering the Intractable More Tractable: Tools from Caenorhabditis elegans Ripe for Import into Parasitic Nematodes.

Authors:  Jordan D Ward
Journal:  Genetics       Date:  2015-12       Impact factor: 4.562

8.  CAP protein superfamily members in Toxocara canis.

Authors:  Andreas J Stroehlein; Neil D Young; Ross S Hall; Pasi K Korhonen; Andreas Hofmann; Paul W Sternberg; Abdul Jabbar; Robin B Gasser
Journal:  Parasit Vectors       Date:  2016-06-24       Impact factor: 3.876

Review 9.  Toxocariasis: a silent threat with a progressive public health impact.

Authors:  Jia Chen; Quan Liu; Guo-Hua Liu; Wen-Bin Zheng; Sung-Jong Hong; Hiromu Sugiyama; Xing-Quan Zhu; Hany M Elsheikha
Journal:  Infect Dis Poverty       Date:  2018-06-13       Impact factor: 4.520

10.  The mitochondrial genome of Parascaris univalens--implications for a "forgotten" parasite.

Authors:  Abdul Jabbar; D Timothy J Littlewood; Namitha Mohandas; Andrew G Briscoe; Peter G Foster; Fritz Müller; Georg von Samson-Himmelstjerna; Aaron R Jex; Robin B Gasser
Journal:  Parasit Vectors       Date:  2014-09-04       Impact factor: 3.876

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