| Literature DB >> 23482667 |
Abstract
Dynamic bone scanning with (99m)Tc-labeled diphosphonates and (18)F-labeled sodium fluoride provides functional information sensitive for subtle changes in bone turnover and perfusion, which assists the clinical management of numerous osseous pathologies. This article reviews the mechanisms of uptake of (99m)Tc-labeled diphosphonates and (18)F-sodium fluoride and discusses and compares the performance of these bone-seeking radiotracers for clinical and research applications, using dynamic and multiple-time-point imaging protocols and quantitative techniques.Entities:
Mesh:
Substances:
Year: 2013 PMID: 23482667 DOI: 10.2967/jnumed.112.114298
Source DB: PubMed Journal: J Nucl Med ISSN: 0161-5505 Impact factor: 10.057