Literature DB >> 2348199

Antineoplastic agents, 162. Zephyranthes candida.

G R Pettit1, G M Cragg, S B Singh, J A Duke, D L Doubek.   

Abstract

The Chinese medicinal plant Zephyranthes candida was found to contain a cytostatic constituent. Separation of a n-BuOH extract directed by results of a bioassay employing the P-388 lymphocytic leukemia led to trans-dihydronarciclasine [2] as the principal cytostatic agent with ED50 3.2 X 10(-3) micrograms/ml.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2348199     DOI： 10.1021/np50067a026

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  14 in total

1.  Two novel ceramides with a phytosphingolipid and a tertiary amide structure from Zephyranthes candida.

Authors:  Zhi-Ping Wu; Yu Chen; Bing Xia; Ming Wang; Yun-Fa Dong; Xu Feng
Journal:  Lipids       Date:  2008-10-22       Impact factor: 1.880

Review 2.  Chemistry, biology, and medicinal potential of narciclasine and its congeners.

Authors:  Alexander Kornienko; Antonio Evidente
Journal:  Chem Rev       Date:  2008-05-20       Impact factor: 60.622

3.  A boron-based synthesis of the natural product (+)-trans-dihydrolycoricidine.

Authors:  Sarah L Poe; James P Morken
Journal:  Angew Chem Int Ed Engl       Date:  2011-03-31       Impact factor: 15.336

4.  TOTAL SYNTHESES OF PANCRATISTATIN. A REVIEW.

Authors:  Madhuri Manpadi; Alexander Kornienko
Journal:  Org Prep Proced Int       Date:  2009-02-18       Impact factor: 1.628

Review 5.  Chemical and biological aspects of Narcissus alkaloids.

Authors:  Jaume Bastida; Rodolfo Lavilla; Francesc Viladomat
Journal:  Alkaloids Chem Biol       Date:  2006

Review 6.  Applications of Friedel-Crafts reactions in total synthesis of natural products.

Authors:  Majid M Heravi; Vahideh Zadsirjan; Pegah Saedi; Tayebeh Momeni
Journal:  RSC Adv       Date:  2018-12-03       Impact factor: 4.036

7.  Amaryllidaceae isocarbostyril alkaloids and their derivatives as promising antitumor agents.

Authors:  Laurent Ingrassia; Florence Lefranc; Véronique Mathieu; Francis Darro; Robert Kiss
Journal:  Transl Oncol       Date:  2008-03       Impact factor: 4.243

8.  Antineoplastic agents. 454. Synthesis of the strong cancer cell growth inhibitors trans-dihydronarciclasine and 7-deoxy-trans-dihydronarciclasine (1a).

Authors:  George R Pettit; Sylvie Ducki; Stephen A Eastham; Noeleen Melody
Journal:  J Nat Prod       Date:  2009-07       Impact factor: 4.050

9.  Cytotoxic alkaloids from the whole plants of Zephyranthes candida.

Authors:  Zengwei Luo; Fuqian Wang; Jinwen Zhang; Xingyao Li; Mengke Zhang; Xincai Hao; Yongbo Xue; Yan Li; F David Horgen; Guangmin Yao; Yonghui Zhang
Journal:  J Nat Prod       Date:  2012-11-28       Impact factor: 4.050

10.  Small molecule activation of NOTCH signaling inhibits acute myeloid leukemia.

Authors:  Qi Ye; Jue Jiang; Guanqun Zhan; Wanyao Yan; Liang Huang; Yufeng Hu; Hexiu Su; Qingyi Tong; Ming Yue; Hua Li; Guangmin Yao; Yonghui Zhang; Hudan Liu
Journal:  Sci Rep       Date:  2016-05-23       Impact factor: 4.379
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.