BACKGROUND: Recognizing the value of outcomes research to understand and bridge translational gaps, to establish evidence in clinical practice and delivery of medicine, and to generate new hypotheses on ongoing questions of treatment and care, the National Heart, Lung, and Blood Institute of the National Institutes of Health established the Centers for Cardiovascular Outcomes Research program in 2010. METHODS AND RESULTS: The National Heart, Lung, and Blood Institute funded 3 centers and a research coordinating unit. Each center has an independent project focus, including (1) characterizing care transition and predicting clinical events and quality of life for patients discharged after an acute coronary syndrome; (2) identifying center and regional factors associated with better patient outcomes across several cardiovascular conditions and procedures; and (3) examining the impact of healthcare reform in Massachusetts on overall and disparate care and outcomes for several cardiovascular conditions and venous thromboembolism. Cross-program collaborations seek to advance the field methodologically and to develop early-stage investigators committed to careers in outcomes research. CONCLUSIONS: The Centers for Cardiovascular Outcomes Research program represents a significant investment in cardiovascular outcomes research by the National Heart, Lung, and Blood Institute. The vision of this program is to leverage scientific rigor and cross-program collaboration to advance the science of healthcare delivery and outcomes beyond what any individual unit could achieve alone.
BACKGROUND: Recognizing the value of outcomes research to understand and bridge translational gaps, to establish evidence in clinical practice and delivery of medicine, and to generate new hypotheses on ongoing questions of treatment and care, the National Heart, Lung, and Blood Institute of the National Institutes of Health established the Centers for Cardiovascular Outcomes Research program in 2010. METHODS AND RESULTS: The National Heart, Lung, and Blood Institute funded 3 centers and a research coordinating unit. Each center has an independent project focus, including (1) characterizing care transition and predicting clinical events and quality of life for patients discharged after an acute coronary syndrome; (2) identifying center and regional factors associated with better patient outcomes across several cardiovascular conditions and procedures; and (3) examining the impact of healthcare reform in Massachusetts on overall and disparate care and outcomes for several cardiovascular conditions and venous thromboembolism. Cross-program collaborations seek to advance the field methodologically and to develop early-stage investigators committed to careers in outcomes research. CONCLUSIONS: The Centers for Cardiovascular Outcomes Research program represents a significant investment in cardiovascular outcomes research by the National Heart, Lung, and Blood Institute. The vision of this program is to leverage scientific rigor and cross-program collaboration to advance the science of healthcare delivery and outcomes beyond what any individual unit could achieve alone.
Authors: Sunil V Rao; Padma Kaul; L Kristin Newby; A Michael Lincoff; Judith Hochman; Robert A Harrington; Daniel B Mark; Eric D Peterson Journal: J Am Coll Cardiol Date: 2003-06-04 Impact factor: 24.094
Authors: Véronique L Roger; Steven J Jacobsen; Susan A Weston; Tauqir Y Goraya; Jill Killian; Guy S Reeder; Thomas E Kottke; Barbara P Yawn; Robert L Frye Journal: Ann Intern Med Date: 2002-03-05 Impact factor: 25.391
Authors: J G Canto; J J Allison; C I Kiefe; C Fincher; R Farmer; P Sekar; S Person; N W Weissman Journal: N Engl J Med Date: 2000-04-13 Impact factor: 91.245
Authors: Arvind Venkat; James Hoekstra; Christopher Lindsell; Dawn Prall; Judd E Hollander; Charles V Pollack; Deborah Diercks; J Douglas Kirk; Brian Tiffany; Frank Peacock; Alan B Storrow; W Brian Gibler Journal: Acad Emerg Med Date: 2003-11 Impact factor: 3.451
Authors: Kim A Eagle; Michael J Lim; Omar H Dabbous; Karen S Pieper; Robert J Goldberg; Frans Van de Werf; Shaun G Goodman; Christopher B Granger; P Gabriel Steg; Joel M Gore; Andrzej Budaj; Alvaro Avezum; Marcus D Flather; Keith A A Fox Journal: JAMA Date: 2004-06-09 Impact factor: 56.272
Authors: Brian C Hiestand; Dawn M Prall; Christopher J Lindsell; James W Hoekstra; Charles V Pollack; Judd E Hollander; Brian R Tiffany; W Frank Peacock; Deborah B Diercks; W Brian Gibler Journal: Acad Emerg Med Date: 2004-04 Impact factor: 3.451
Authors: David D McManus; Jane S Saczynski; Darleen Lessard; Molly E Waring; Jeroan Allison; David C Parish; Robert J Goldberg; Arlene Ash; Catarina I Kiefe Journal: Am J Cardiol Date: 2015-12-02 Impact factor: 2.778
Authors: Robert J Goldberg; Jane S Saczynski; David D McManus; Molly E Waring; Richard McManus; Jeroan Allison; David C Parish; Darleen Lessard; Sharina Person; Joel M Gore; Catarina I Kiefe Journal: Am J Med Date: 2015-05-23 Impact factor: 4.965
Authors: Mayra Tisminetzky; Jerry Gurwitz; David D McManus; Jane S Saczynski; Nathaniel Erskine; Molly E Waring; Milena Anatchkova; Hamza Awad; David C Parish; Darleen Lessard; Catarina Kiefe; Robert Goldberg Journal: Am J Med Date: 2015-12-20 Impact factor: 4.965
Authors: Nihar R Desai; Craig S Parzynski; Harlan M Krumholz; Karl E Minges; John C Messenger; Brahmajee K Nallamothu; Jeptha P Curtis Journal: JAMA Intern Med Date: 2015-12 Impact factor: 21.873
Authors: Robert J Goldberg; Joel M Gore; David D McManus; Richard McManus; Mayra Tisminetzky; Darleen Lessard; Jerry H Gurwitz; David C Parish; Jeroan Allison; Connie Ng Hess; Tracy Wang; Catarina Kiefe Journal: Prev Med Rep Date: 2017-01-24