Literature DB >> 23481107

Otitis media.

Michael E Pichichero1.   

Abstract

Acute otitis media (AOM) is diagnosed based on visualization of a full or bulging tympanic membrane with middle ear effusion. The distribution of bacteria causing AOM in North America under the influence of pneumococcal conjugate vaccination and antibiotic selection pressure has resulted in a predominance of β-lactamase-producing Haemophilus influenzae followed by penicillin-resistant Streptococcus pneumoniae. Although guidelines continue to endorse amoxicillin as the preferred treatment, amoxicillin/clavulanate in high dosage would be the preferred treatment based on the otopathogen mix currently. Antibiotic prophylaxis has fallen into disfavor as a preventative strategy for AOM recurrences.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID: 23481107     DOI: 10.1016/j.pcl.2012.12.007

Source DB:  PubMed          Journal:  Pediatr Clin North Am        ISSN: 0031-3955            Impact factor:   3.278


  30 in total

1.  Correlation of higher antibody levels to pneumococcal proteins with protection from pneumococcal acute otitis media but not protection from nasopharyngeal colonization in young children.

Authors:  Q Xu; J R Casey; A Almudevar; M E Pichichero
Journal:  Clin Microbiol Infect       Date:  2017-01-28       Impact factor: 8.067

2.  Serological criteria and carriage measurement for evaluation of new pneumococcal vaccines.

Authors:  Nicola Principi; Susanna Esposito
Journal:  Hum Vaccin Immunother       Date:  2015       Impact factor: 3.452

3.  Serum antibody response to Moraxella catarrhalis proteins in stringently defined otitis prone children.

Authors:  Dabin Ren; Anthony L Almudevar; Timothy F Murphy; Eric R Lafontaine; Anthony A Campagnari; Nicole Luke-Marshall; Michael E Pichichero
Journal:  Vaccine       Date:  2017-07-26       Impact factor: 3.641

4.  Resistance of non-typeable Haemophilus influenzae biofilms is independent of biofilm size.

Authors:  Jennifer L Reimche; Daniel J Kirse; Amy S Whigham; W Edward Swords
Journal:  Pathog Dis       Date:  2016-12-11       Impact factor: 3.166

5.  Biofilm biology and vaccine strategies for otitis media due to nontypeable Haemophilus influenzae.

Authors:  Laura A Novotny; Kenneth L Brockman; Elaine M Mokrzan; Joseph A Jurcisek; Lauren O Bakaletz
Journal:  J Pediatr Infect Dis       Date:  2018-07-06       Impact factor: 0.293

6.  Epidemiology of Acute Otitis Media in the Postpneumococcal Conjugate Vaccine Era.

Authors:  Ravinder Kaur; Matthew Morris; Michael E Pichichero
Journal:  Pediatrics       Date:  2017-08-07       Impact factor: 7.124

7.  Differential impact of respiratory syncytial virus and parainfluenza virus on the frequency of acute otitis media is explained by lower adaptive and innate immune responses in otitis-prone children.

Authors:  David Verhoeven; Qingfu Xu; Michael E Pichichero
Journal:  Clin Infect Dis       Date:  2014-04-29       Impact factor: 9.079

8.  Poor memory B cell generation contributes to non-protective responses to DTaP vaccine antigens in otitis-prone children.

Authors:  S Basha; M E Pichichero
Journal:  Clin Exp Immunol       Date:  2015-09-30       Impact factor: 4.330

Review 9.  Role of innate immunity in the pathogenesis of otitis media.

Authors:  Rahul Mittal; Joyson Kodiyan; Robert Gerring; Kalai Mathee; Jian-Dong Li; M'hamed Grati; Xue Zhong Liu
Journal:  Int J Infect Dis       Date:  2014-11-05       Impact factor: 3.623

10.  Human antibodies to PhtD, PcpA, and Ply reduce adherence to human lung epithelial cells and murine nasopharyngeal colonization by Streptococcus pneumoniae.

Authors:  Ravinder Kaur; Naveen Surendran; Martina Ochs; Michael E Pichichero
Journal:  Infect Immun       Date:  2014-09-22       Impact factor: 3.441

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