BACKGROUND/ OBJECTIVE: Renal failure remains one of the most significant causes of morbidity in patients with anorectal malformations (ARM). In the modern era, an increasing number of children born with ARM and genito-urinary (GU) anomalies reach adulthood and require continued multidisciplinary care for the rest of their life. The aim of this study is to present our institutional experience in the management of pediatric chronic renal failure related to severe GU anomalies and anorectal malformations. METHODS AND RESULTS: Three hundred twenty-one patients with ARM have been followed at our institution since 1987. Six patients developed end-stage renal disease (ESRD) and received a kidney transplant at different ages. One patient is currently followed for mild, progressive chronic renal failure. These seven cases are reported along with a broad discussion concerning etiology of renal failure, neonatal surgical management, pediatric dialysis, urologic issues, and kidney transplantation. CONCLUSION: Complex GU anomalies associated with ARM require a long-term approach by specialized pediatric and adult clinicians to optimize the care of this selected population of patients.
BACKGROUND/ OBJECTIVE:Renal failure remains one of the most significant causes of morbidity in patients with anorectal malformations (ARM). In the modern era, an increasing number of children born with ARM and genito-urinary (GU) anomalies reach adulthood and require continued multidisciplinary care for the rest of their life. The aim of this study is to present our institutional experience in the management of pediatric chronic renal failure related to severe GU anomalies and anorectal malformations. METHODS AND RESULTS: Three hundred twenty-one patients with ARM have been followed at our institution since 1987. Six patients developed end-stage renal disease (ESRD) and received a kidney transplant at different ages. One patient is currently followed for mild, progressive chronic renal failure. These seven cases are reported along with a broad discussion concerning etiology of renal failure, neonatal surgical management, pediatric dialysis, urologic issues, and kidney transplantation. CONCLUSION: Complex GU anomalies associated with ARM require a long-term approach by specialized pediatric and adult clinicians to optimize the care of this selected population of patients.
Authors: Andrea Bischoff; William DeFoor; Brian VanderBrink; Jens Goebel; Jennifer Hall; Maria Alonso; Pramod Reddy; Alberto Peña Journal: Pediatr Surg Int Date: 2015-07-05 Impact factor: 1.827
Authors: Marina L Reppucci; Lea A Wehrli; Duncan Wilcox; Jill Ketzer; Alberto Pena; Luis de la Torre; Andrea Bischoff; Dan Wood Journal: Pediatr Surg Int Date: 2022-09-23 Impact factor: 2.003
Authors: Eugene Y H Chan; Dagmara Borzych-Duzalka; Caner Alparslan; Elizabeth Harvey; Reyner Loza Munarriz; Dariusz Runowski; Enrico Vidal; Paula A Coccia; Augustina Jankauskiene; Iliana Principi; Erkin Serdaroglu; Maria Szczepanska; Yincent Tse; Aida Vazquez; Donald J Weaver; Franz Schaefer; Bradley A Warady Journal: Pediatr Nephrol Date: 2019-10-30 Impact factor: 3.714