Literature DB >> 2348070

Effects of indomethacin on adhesion formation after repair of zone II tendon lacerations in the rabbit.

R M Szabo1, E Younger.   

Abstract

The flexor digitorum profundus tendon of the second medial toe of the hind foot was completely divided and repaired in zone II in 30 New Zealand white rabbits. Half of the animals received indomethacin solution (1 mg/kg/day) injected subcutaneously 2 hours before operation and daily for 4 weeks. The remaining 15 animals received daily injection of the same volume of saline solution. At 4 weeks the animals were killed and measurements were made of the angular motion of the distal interphalangeal joint and the excursion of the tendon. The animals treated with indomethacin had a greater tendon excursion and angular rotation of the joint than the control animals, implying a suppression of adhesions.

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Year:  1990        PMID： 2348070     DOI： 10.1016/0363-5023(90)90066-z

Source DB:  PubMed          Journal:  J Hand Surg Am        ISSN： 0363-5023            Impact factor:   2.230


  10 in total

1.  Effects of non-steroidal anti-inflammatory drugs on flexor tendon rehabilitation after repair.

Authors:  Alireza Rouhani; Ali Tabrizi; Ehsan Ghavidel
Journal:  Arch Bone Jt Surg       Date:  2013-09-15

2.  Sodium hyaluronate regulating angiogenesis during Achilles tendon healing.

Authors:  Mehmet Halici; Sinan Karaoglu; Ozlem Canoz; Sevki Kabak; Ali Baktir
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2004-07-27       Impact factor: 4.342

3.  Prevention of Postoperative Peritendinous Adhesions with Bioresorbable Suprathel Barrier Membrane.

Authors:  Paul S Wiggenhauser; Nikolaus Wachtel; Konstantin C Koban; Riccardo E Giunta; Andreas Frick; Denis Ehrl
Journal:  Plast Reconstr Surg Glob Open       Date:  2022-06-08

4.  Prevention of peritendinous adhesions using a hyaluronan-derived hydrogel film following partial-thickness flexor tendon injury.

Authors:  Yanchun Liu; Aleksander Skardal; Xiao Zheng Shu; Glenn D Prestwich
Journal:  J Orthop Res       Date:  2008-04       Impact factor: 3.494

5.  Localized delivery of ibuprofen via a bilayer delivery system (BiLDS) for supraspinatus tendon healing in a rat model.

Authors:  Brittany L Taylor; Dong Hwa Kim; Julianne Huegel; Harina A Raja; Sophie J Burkholder; Stephanie N Weiss; Courtney A Nuss; Louis J Soslowsky; Robert L Mauck; Andrew F Kuntz; Joseph Bernstein
Journal:  J Orthop Res       Date:  2020-04-07       Impact factor: 3.494

6.  A new material for prevention of peritendinous fibrotic adhesions after tendon repair: oxidised regenerated cellulose (Interceed), an absorbable adhesion barrier.

Authors:  A Temiz; C Ozturk; A Bakunov; K Kara; T Kaleli
Journal:  Int Orthop       Date:  2007-03-09       Impact factor: 3.075

Review 7.  Prospective application of stem cells to prevent post-operative skeletal fibrosis.

Authors:  Xiaolei Li; Song Chen; Lianqi Yan; Jingcheng Wang; Ming Pei
Journal:  J Orthop Res       Date:  2019-03-21       Impact factor: 3.102

8.  Biomechanical and Macroscopic Evaluations of the Effects of 5-Fluorouracil on Partially Divided Flexor Tendon Injuries in Rabbits.

Authors:  Shkelzen B Duci; Hysni M Arifi; Hasan R Ahmeti; Suzana Manxhuka-Kerliu; Burim Neziri; Agon Y Mekaj; Shpetim Lajqi; Labinot Shahini
Journal:  Chin Med J (Engl)       Date:  2015-06-20       Impact factor: 2.628

9.  Effect of Acellular Amnion With Increased TGF-β and bFGF Levels on the Biological Behavior of Tenocytes.

Authors:  Rongli Sang; Yuanyuan Liu; Lingyu Kong; Ligang Qian; Chunjie Liu
Journal:  Front Bioeng Biotechnol       Date:  2020-05-14

Review 10.  NSAID therapy effects on healing of bone, tendon, and the enthesis.

Authors:  Bailey Su; J Patrick O'Connor
Journal:  J Appl Physiol (1985)       Date:  2013-07-18
  10 in total

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