Literature DB >> 23480630

Time to diagnosis of brain tumors in children: a single-centre experience.

Anja Molineus1, Nicole Boxberger, Antje Redlich, Peter Vorwerk.   

Abstract

BACKGROUND: The aim of the study was to analyze the pre-diagnostic symptomatic interval (PSI) of children with brain tumors with regard to the parental and doctor's delay and the clinical symptoms.
METHODS: A retrospective review of all children with brain tumors diagnosed in a single centre over a period of 11 years was carried out.
RESULTS: Seventy-nine patients (35 boys, 44 girls), with a mean age of 9.2 years (0.2-23.5 years), were analyzed. PSI was 28 weeks with a parental delay of 11.1 weeks and a doctor's delay of 16.9 weeks. Main clinical symptoms were headache (66.7%), vomiting (57.7%), vision (46.2%) and gait (41.6) disorders and fatigue (41.0%) followed by other neurological signs.
CONCLUSIONS: Diagnosis of pediatric brain tumors is often delayed in relation to the presenting symptoms. If parents report a combination of headache with other neurological abnormalities, a brain tumor should always be considered.
© 2013 The Authors. Pediatrics International © 2013 Japan Pediatric Society.

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Year:  2013        PMID: 23480630     DOI: 10.1111/ped.12095

Source DB:  PubMed          Journal:  Pediatr Int        ISSN: 1328-8067            Impact factor:   1.524


  4 in total

Review 1.  Case-based review: pediatric medulloblastoma.

Authors:  Cassie N Kline; Roger J Packer; Eugene I Hwang; David R Raleigh; Steve Braunstein; Corey Raffel; Pratiti Bandopadhayay; David A Solomon; Mariam Aboian; Soonmee Cha; Sabine Mueller
Journal:  Neurooncol Pract       Date:  2017-08-11

2.  The Role of Time as a Prognostic Factor in Pediatric Brain Tumors: a Multivariate Survival Analysis.

Authors:  Eduardo Javier Barragán-Pérez; Carlos Enrique Altamirano-Vergara; Daniel Eduardo Alvarez-Amado; Juan Carlos García-Beristain; Fernando Chico-Ponce-de-León; Vicente González-Carranza; Luis Juárez-Villegas; Chiharu Murata
Journal:  Pathol Oncol Res       Date:  2020-07-13       Impact factor: 2.874

3.  Experts' opinion about the pediatric secondary headaches diagnostic criteria of the ICHD-3 beta.

Authors:  Aynur Özge; Ishaq Abu-Arafeh; Amy A Gelfand; Peter James Goadsby; Jean Christophe Cuvellier; Massimiliano Valeriani; Alexey Sergeev; Karen Barlow; Derya Uludüz; Osman Özgür Yalın; Noemi Faedda; Richard B Lipton; Alan Rapoport; Vincenzo Guidetti
Journal:  J Headache Pain       Date:  2017-11-29       Impact factor: 7.277

4.  Clinical presentation of young people (10-24 years old) with brain tumors: results from the international MOBI-Kids study.

Authors:  Angela Zumel-Marne; Michael Kundi; Gemma Castaño-Vinyals; Juan Alguacil; Eleni Th Petridou; Marios K Georgakis; Maria Morales-Suárez-Varela; Siegal Sadetzki; Sara Piro; Rajini Nagrani; Graziella Filippini; Hans-Peter Hutter; Rajesh Dikshit; Adelheid Woehrer; Milena Maule; Tobias Weinmann; Daniel Krewski; Andrea T Mannetje; Franco Momoli; Brigitte Lacour; Stefano Mattioli; John J Spinelli; Paul Ritvo; Thomas Remen; Noriko Kojimahara; Amanda Eng; Angela Thurston; Hyungryul Lim; Mina Ha; Naohito Yamaguchi; Charmaine Mohipp; Evdoxia Bouka; Chelsea Eastman; Roel Vermeulen; Hans Kromhout; Elisabeth Cardis
Journal:  J Neurooncol       Date:  2020-03-03       Impact factor: 4.130

  4 in total

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