| Literature DB >> 23480610 |
Emrys A Jones1, Nicole Schmitz, Cathelijn J F Waaijer, Christian K Frese, Alexandra van Remoortere, René J M van Zeijl, Albert J R Heck, Pancras C W Hogendoorn, André M Deelder, A F Maarten Altelaar, Judith V M G Bovée, Liam A McDonnell.
Abstract
Many tumors display significant cellular heterogeneity as well as molecular heterogeneity. Sensitive biomarkers that differentiate between diagnostically challenging tumors must contend with this heterogeneity. Mass spectrometry-based molecular histology of a patient series of heterogeneous, microscopically identical bone tumors highlighted the tumor cell types that could be characterized by a single profile and led to the identification of specific peptides that differentiate between the tumors.Entities:
Mesh：
Year: 2013 PMID： 23480610 DOI： 10.1021/pr301190g
Source DB: PubMed Journal: J Proteome Res ISSN： 1535-3893 Impact factor: 4.466