| Literature DB >> 2347964 |
G A Ksander1, S J Sawamura, Y Ogawa, J Sundsmo, J M McPherson.
Abstract
The alpha granules of platelets contain growth factors that are important in wound healing. We found that a major effect of thrombin-induced human platelet releasates in animal models of wound healing is to enhance the development of granulation tissue and new connective tissue matrix. These studies provide further evidence that platelet-derived protein factors may be useful in treating full-thickness dermal wounds by increasing the rate of granulation tissue formation.Entities:
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Year: 1990 PMID： 2347964 DOI： 10.1016/0190-9622(90)70109-u
Source DB: PubMed Journal: J Am Acad Dermatol ISSN： 0190-9622 Impact factor: 11.527