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Literature DB >> 23478014

Chelators for investigating zinc metalloneurochemistry.

Abstract

The physiology and pathology of mobile zinc signaling has become an important topic in metalloneurochemistry. To study the action of mobile zinc effectively, specialized tools are required that probe the temporal and positional changes of zinc ions within live tissue and cells. In the present article we describe the design and implementation of selective zinc chelators as antagonists to interrogate the function of mobile zinc, with an emphasis on the pools of vesicular zinc in the terminals of hippocampal mossy fiber buttons.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：
Chelating Agents
Zinc

Year: 2013 PMID： 23478014 PMCID： PMC3634875 DOI： 10.1016/j.cbpa.2013.01.009

Source DB: PubMed Journal: Curr Opin Chem Biol ISSN： 1367-5931 Impact factor: 8.822

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