Squamous cell carcinoma of the vulva in a cow.

An 8-year-old Holstein cow was evaluated because of a slowly enlarging vulvar mass that had impaired artificial insemination attempts. Vulvar squamous cell carcinoma was diagnosed. Clinical cases of vulvar squamous cell carcinoma have not been as widely reported as those of ocular squamous cell carcinoma in cattle. Treatment modalities for vulvar squamous cell carcinoma have not been as thoroughly investigated as for those of the ocular condition. Cryosurgery and radio-frequency hyperthermia appear to be the optimal therapeutic modalities, each providing up to 90% tumor remission.